Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 7/20 | 0.40 |
| ▸ | SRC | P12931 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | COMT | P21964 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | WEE1 | P30291 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31743108 | 0.73 | MAT2A (0.48) | FGFR1SRCHSD17B10HPGDHTT | |
| SCHEMBL22004332 | 0.70 | ACLY (0.47) | HSD17B10HPGDGPR35ACLYTSHR | |
| SCHEMBL17813481 | 0.68 | KMO (0.44) | DAOEGFR | |
| SCHEMBL30692889 | 0.65 | CA12 (0.52) | HSD17B10HPGDDAO | |
| SCHEMBL8229991 | 0.65 | CA12 (0.52) | HSD17B10HPGDDAO | |
| SCHEMBL29714935 | 0.64 | CDC7 (0.44) | HSD17B10 | |
| SCHEMBL29499630 | 0.63 | MEN1 (0.41) | HSD17B10HPGDHTTMAT2ATSHR | |
| SCHEMBL20569436 | 0.62 | CYP19A1 (0.52) | HPGD | |
| SCHEMBL30884990 | 0.62 | FGFR1 (0.41) | FGFR1SRCHSD17B10HPGDHTT | |
| SCHEMBL22753168 | 0.62 | HPGD (0.33) | HSD17B10HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118829642-A | Diacylglycerol kinase (DGK) alpha inhibitors and uses thereof | 英矽智能科技知识产权有限公司 | 2024-10-22 | — | — | CN | disclosed |