Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 10/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | HK2 | P52789 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3132323 | 0.75 | CYP3A4 (0.39) | PKMLMNAHTTPTGS2 | |
| SCHEMBL5820540 | 0.75 | PTGS2 (0.39) | PKMLMNAHTTPTGS2MAOA | |
| SCHEMBL5821593 | 0.69 | PTGS2 (0.39) | PKMLMNAHTTEGFRPTGS2 | |
| SCHEMBL3147213 | 0.65 | CYP3A4 (0.39) | PKMLMNAHTTPTGS2MEN1 | |
| SCHEMBL5820346 | 0.64 | MEN1 (0.47) | PKMLMNAHTTEGFRPTGS2 | |
| SCHEMBL28813544 | 0.63 | PKM (0.47) | PKMLMNAHTTPTGS2MEN1 | |
| SCHEMBL31536865 | 0.62 | COPS5 (0.40) | COPS5 | |
| Austrocortirubin SCHEMBL23199031 | 0.62 | LCK (0.56) | EGFRMAOAMEN1NPC1MAPT | |
| Austrocortirubin SCHEMBL29357393 | 0.62 | LCK (0.56) | EGFRMAOAMEN1NPC1MAPT | |
| SCHEMBL19303777 | 0.62 | EGFR (0.38) | LMNAHTTEGFRMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867394-B9 | Anti-VLA-4 antibodies with reduced effector function | 马萨诸塞州渤健公司 | 2024-12-06 | — | — | CN | disclosed |
| CN-119080931-A | Anti-VLA-4 antibodies with reduced effector function | 马萨诸塞州渤健公司 | 2024-12-06 | — | — | CN | disclosed |