SCHEMBL3147213

SCHEMBL3147213

COc1cc(O)c2c(c1O)C(=O)C(CC(C)=O)=C(C)C2=O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 3/20 0.39
▸ KDM4E B2RXH2 2/20 0.38
▸ MEN1 O00255 2/20 0.38
▸ MAPT P10636 2/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ USP2 O75604 1/20 0.38
▸ LMNA P02545 1/20 0.37
▸ CYP1A2 P05177 1/20 0.37
▸ CYP2D6 P10635 1/20 0.37
▸ CYP2C9 P11712 1/20 0.37
▸ CYP2B6 P20813 1/20 0.37
▸ TNKS2 Q9H2K2 1/20 0.36
▸ HTT P42858 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ HPGD P15428 1/20 0.36
▸ RECQL P46063 1/20 0.36
▸ PTGS2 P35354 2/20 0.36
▸ FASN P49327 1/20 0.35
▸ PIM1 P11309 1/20 0.35
▸ ALOX5 P09917 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3132323 0.76 CYP3A4 (0.39) CYP3A4LMNACYP1A2CYP2D6CYP2C9
SCHEMBL23198970 0.70 MAPT (0.47) CYP3A4KDM4EMEN1MAPTKMT2A
SCHEMBL5820346 0.69 MEN1 (0.47) CYP3A4KDM4EMEN1MAPTKMT2A
SCHEMBL29709363 0.69 PIM1 (0.69) CYP3A4KDM4EMEN1MAPTKMT2A
Austrocortirubin SCHEMBL23199031 0.68 LCK (0.56) CYP3A4KDM4EMEN1MAPTKMT2A
Austrocortirubin SCHEMBL29357393 0.68 LCK (0.56) CYP3A4KDM4EMEN1MAPTKMT2A
SCHEMBL23199058 0.67 PIM1 (0.49) CYP3A4KDM4EMEN1MAPTKMT2A
SCHEMBL5821593 0.66 PTGS2 (0.39) CYP3A4KDM4EMEN1MAPTKMT2A
SCHEMBL5820540 0.66 PTGS2 (0.39) CYP3A4KDM4EMEN1MAPTKMT2A
SCHEMBL18971654 0.66 STAT3 (0.54) CYP3A4KDM4EMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 — — US claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 — — US claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 — — WO claimed
WO-2022182523-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2022-09-01 — — WO claimed
WO-2021158573-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 — — WO claimed
WO-2021158575-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 — — WO claimed
WO-2021042001-A1 COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES Natural Extraction Systems, LLC (US) 2021-03-04 — — WO claimed
US-20260048025-A1 COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES NATURAL EXTRACTION SYS LLC (US) 2026-02-19 — — US disclosed
US-20250360073-A1 SOLUBILIZING PIGMENTS EXTRACTED FROM FUNGI FOR APPLICATIONS SUCH AS COSMETIC PRODUCTS ADLER JESSE (US) 2025-11-27 — — US disclosed
US-12409152-B2 Compositions and methods related to dissolved oxides Natural Extraction Systems, LLC (US) 2025-09-09 — — US disclosed
US-20250161394-A1 Compositions Comprising Kavalactones NATURAL EXTRACTION SYS LLC (US) 2025-05-22 — — US disclosed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 — — US disclosed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 — — US disclosed
WO-2002100478-A2 ACCELERATORS FOR INCREASING THE RATE OF FORMATION OF FREE RADICALS AND REACTIVE OXYGEN SPECIES CAVALIER DISCOVERY (US) 2002-12-19 — — WO disclosed
EP-1261254-A2 METHOD OF CONTROLLING ZOOLOGICAL AND AQUATIC PLANT GROWTH Garnett, Inc. (US) 2002-12-04 — — EP disclosed
US-20020098979-A1 Method of controlling zoological and aquatic plant growth CUTLER STEPHEN J (US) 2002-07-25 — — US disclosed
US-20020098978-A1 Method of controlling zoological and aquatic plant growth CUTLER STEPHEN J (US) 2002-07-25 — — US disclosed
US-6340468-B1 KILLING A TARGET AQUATIC PEST SELECTED FROM VIRUSES, PROTISTS, FUNGI, MOLDS, PLANTS, HOLOPLANKTONIC ORGANISMS, MEROPLANKTONIC ORGANISMS, DEMERSAL ORGANISMS, BENTHIC ORGANISMS, ECT., BY APPLYING NAPHTHALENEDIONE COMPOUND GARNETT, INC. 2002-01-22 — — US disclosed
WO-2001060971-A2 METHOD OF CONTROLLING ZOOLOGICAL AND AQUATIC PLANT GROWTH GARNETT, INC. (US) 2001-08-23 — — WO disclosed
EP-0234431-A2 5-Hydroxydihydrofusarubin, a process for its preparation and its use for the preparation of a medicament HOECHST JAPAN LIMITED (JP) 1987-09-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB CYP3A4 3571/4885KDM4E 4637/4885MEN1 1711/4885
US-20020098978-A1 Method of controlling zoological and aquatic plant growth ANTXR2, AQP1, AQP3 CYP3A4 2936/4885KDM4E 3300/4885MEN1 3800/4885
US-12409152-B2 Compositions and methods related to dissolved oxides PRKG2, PRKG1, CIT CYP3A4 3252/4885KDM4E 4365/4885MEN1 593/4885
US-20020098979-A1 Method of controlling zoological and aquatic plant growth ANTXR2, NQO2, CYP4A22 CYP3A4 164/4885KDM4E 2692/4885MEN1 3909/4885
US-20260048025-A1 COMPOSITIONS AND METHODS RELATED TO DISSOLVED OXIDES SCO2, CNR2, CNR1 CYP3A4 1840/4885KDM4E 3795/4885MEN1 1906/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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