Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 3/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184468 | 0.89 | TP53 (0.44) | MAPK1TSHRKMT2ATYK2IDO1 | |
| SCHEMBL31184812 | 0.85 | MGLL (0.48) | MAPK1TSHRKMT2APOLBMAPT | |
| SCHEMBL31184751 | 0.85 | MTNR1A (0.53) | TSHRKMT2AIDO1TDO2MAPT | |
| SCHEMBL31184640 | 0.84 | POLB (0.45) | MAPK1TSHRKMT2ATYK2POLB | |
| SCHEMBL31184475 | 0.84 | POLB (0.49) | MAPK1KMT2APOLBMAPTLMNA | |
| SCHEMBL31184972 | 0.84 | POLB (0.44) | MAPK1TSHRKMT2ATYK2POLB | |
| SCHEMBL31184809 | 0.84 | MAPK1 (0.42) | MAPK1TSHRKMT2AIDO1TDO2 | |
| SCHEMBL31184761 | 0.83 | MAPT (0.43) | MAPK1TSHRKMT2ATYK2POLB | |
| SCHEMBL31184979 | 0.82 | ALDH1A1 (0.46) | MAPK1TSHRKMT2APOLBMAPT | |
| SCHEMBL31185026 | 0.81 | KMT2A (0.48) | MAPK1TSHRKMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |