Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA4 | P22748 | 3/20 | 0.35 |
| ▸ | CA6 | P23280 | 3/20 | 0.35 |
| ▸ | CA7 | P43166 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | NEK2 | P51955 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184718 | 0.82 | MAPT (0.43) | KDM1A | |
| SCHEMBL31184632 | 0.81 | MAPK1 (0.46) | MAPK1BTKALDH1A1IDH1 | |
| SCHEMBL31184585 | 0.80 | CHKA (0.44) | MAPK1LMNAALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL31184750 | 0.78 | BTK (0.34) | KDM1ABTKALDH1A1 | |
| SCHEMBL31184702 | 0.77 | POLB (0.40) | MAPK1LMNAALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL13719272 | 0.74 | CRBN (0.39) | BTKNPY1RNPY5R | |
| SCHEMBL31184880 | 0.73 | MAPK1 (0.45) | MAPK1BTKALDH1A1IDH1 | |
| SCHEMBL31184821 | 0.73 | MAPT (0.42) | CA1CA2CA4CA6LMNA | |
| SCHEMBL31184661 | 0.70 | ALDH1A1 (0.34) | KDM1AHSP90AA1BTKALDH1A1CYP3A4 | |
| SCHEMBL31184452 | 0.68 | MAPK1 (0.51) | MAPK1ALDH1A1IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |