Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184880 | 0.87 | MAPK1 (0.45) | MAPK1HTR2AHTR2CHTR2BIDH1 | |
| SCHEMBL31184529 | 0.86 | MAPK1 (0.49) | MAPK1HTR2AHTR2CHTR2BIDH1 | |
| SCHEMBL31184452 | 0.85 | MAPK1 (0.51) | MAPK1HTR2AHTR2CHTR2BIDH1 | |
| SCHEMBL31184816 | 0.85 | MAPK1 (0.48) | MAPK1HTR2AHTR2CHTR2BIDH1 | |
| SCHEMBL31184698 | 0.81 | CHRM4 (0.36) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL31184494 | 0.81 | KDM1A (0.39) | MAPK1IDH1ALDH1A1BTK | |
| SCHEMBL31184630 | 0.81 | HPGD (0.44) | MAPK1RAB9ABTK | |
| SCHEMBL31184751 | 0.80 | MTNR1A (0.53) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL31185026 | 0.80 | KMT2A (0.48) | MAPK1MEN1KMT2ARAB9AALDH1A1 | |
| SCHEMBL31184979 | 0.79 | ALDH1A1 (0.46) | MAPK1MEN1KMT2ARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |