Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184698 | 0.82 | CHRM4 (0.36) | ALDH1A1SMN1; SMN2BTKJAK2KDM4E | |
| SCHEMBL31184365 | 0.81 | POLB (0.42) | ALDH1A1HTTSMN1; SMN2CYP3A4CYP2C19 | |
| SCHEMBL31184574 | 0.79 | ACE (0.37) | ALDH1A1HTTSMN1; SMN2BTKSLC6A2 | |
| SCHEMBL31184729 | 0.78 | POLB (0.39) | ALDH1A1HTTSMN1; SMN2CYP3A4CYP2C19 | |
| SCHEMBL31184505 | 0.78 | POLB (0.39) | ALDH1A1HTTSMN1; SMN2CYP3A4CYP2C19 | |
| SCHEMBL31184692 | 0.74 | JAK2 (0.39) | SMN1; SMN2JAK2KDM1AKDM4E | |
| SCHEMBL31184494 | 0.70 | KDM1A (0.39) | ALDH1A1BTKCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31184907 | 0.68 | JAK2 (0.40) | JAK2 | |
| SCHEMBL31184632 | 0.68 | MAPK1 (0.46) | ALDH1A1BTK | |
| SCHEMBL31184880 | 0.67 | MAPK1 (0.45) | ALDH1A1HTTSMN1; SMN2BTKSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |