Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | CXCR6 | O00574 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184599 | 0.90 | MEN1 (0.40) | CACNA1HKMT2AMEN1RAB9ALMNA | |
| SCHEMBL31185055 | 0.82 | ALDH1A1 (0.46) | CXCR6KMT2AMEN1RAB9ALMNA | |
| SCHEMBL31184453 | 0.77 | GRM1 (0.40) | KMT2AMEN1GRM1MALT1GAA | |
| SCHEMBL31184345 | 0.74 | POLB (0.42) | KMT2ARAB9ALMNAGRM1MALT1 | |
| SCHEMBL31184754 | 0.74 | MAPT (0.47) | KMT2ARAB9ALMNAGRM1L3MBTL1 | |
| SCHEMBL31185096 | 0.74 | FPR2 (0.38) | KMT2AMEN1GRM1ALDH1A1GAA | |
| SCHEMBL31184905 | 0.73 | GRM1 (0.40) | GRM1MALT1ALDH1A1GAAATM | |
| SCHEMBL31184873 | 0.73 | GAA (0.41) | LMNAGRM1ALDH1A1GAAL3MBTL1 | |
| SCHEMBL31184462 | 0.72 | CYP3A4 (0.40) | KMT2ARAB9ALMNAMALT1ALDH1A1 | |
| SCHEMBL31184716 | 0.66 | NPSR1 (0.47) | KMT2AMEN1RAB9ALMNAMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |