Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | F13A1 | P00488 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | TGM1 | P22735 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.33 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184873 | 0.92 | GAA (0.41) | GAAATMGRM1MAPTL3MBTL1 | |
| SCHEMBL31184875 | 0.79 | FPR2 (0.44) | FPR2 | |
| SCHEMBL31184345 | 0.77 | POLB (0.42) | GRM1MAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL31184754 | 0.76 | MAPT (0.47) | GRM1MAPTL3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL31184453 | 0.74 | GRM1 (0.40) | GAAATMGRM1MAPTMEN1 | |
| SCHEMBL31184772 | 0.74 | EHMT2 (0.38) | FPR2MAPTF13A1TGM2TGM1 | |
| SCHEMBL31184599 | 0.74 | MEN1 (0.40) | GAAATMGRM1MAPTTHRB | |
| SCHEMBL31184905 | 0.72 | GRM1 (0.40) | GAAATMGRM1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31184482 | 0.70 | TP53 (0.48) | FPR2MAPTL3MBTL1THRB | |
| SCHEMBL31184839 | 0.70 | IDH1 (0.39) | GAAGRM1L3MBTL1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |