Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184816 | 0.88 | MAPK1 (0.48) | MAPK1HTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL31184452 | 0.88 | MAPK1 (0.51) | MAPK1HTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL31184632 | 0.86 | MAPK1 (0.46) | MAPK1HTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL31185026 | 0.81 | KMT2A (0.48) | MAPK1MEN1KMT2AMAPT | |
| SCHEMBL31184979 | 0.80 | ALDH1A1 (0.46) | MAPK1MEN1KMT2AMAPT | |
| SCHEMBL31184907 | 0.80 | JAK2 (0.40) | MEN1KMT2AMAPT | |
| SCHEMBL31184422 | 0.79 | MAPK1 (0.40) | MAPK1HTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL31185049 | 0.78 | ALDH1A1 (0.44) | MAPK1KMT2ACRBNMAPT | |
| SCHEMBL31184891 | 0.78 | KMT2A (0.52) | MAPK1MEN1KMT2A | |
| SCHEMBL31184657 | 0.78 | ALDH1A1 (0.44) | MAPK1KMT2ACRBNMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |