Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | CALCA | P06881 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184698 | 0.87 | CHRM4 (0.36) | ACEMMP13ALDH1A1SMN1; SMN2CDK5 | |
| SCHEMBL31184880 | 0.81 | MAPK1 (0.45) | ALDH1A1HTTSMN1; SMN2BTKSLC6A4 | |
| SCHEMBL31184597 | 0.79 | POLB (0.41) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL31184661 | 0.79 | ALDH1A1 (0.34) | ALDH1A1HTTSMN1; SMN2BTKSLC6A4 | |
| SCHEMBL31184907 | 0.74 | JAK2 (0.40) | ACEMMP13CDK5CDK5R1CHRM4 | |
| SCHEMBL31184632 | 0.71 | MAPK1 (0.46) | ALDH1A1BTKALOX15 | |
| SCHEMBL2866213 | 0.69 | MAPK1 (0.52) | HTTCDK5CDK5R1CALCRL | |
| SCHEMBL28497393 | 0.69 | HSD11B1 (0.46) | ALDH1A1HSD11B1CHRM4CHRM1 | |
| SCHEMBL28497394 | 0.69 | HSD11B1 (0.46) | ALDH1A1HSD11B1CHRM4CHRM1 | |
| SCHEMBL4613887 | 0.68 | BRD4 (0.56) | ACEMMP13CDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |