Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184657 | 0.84 | ALDH1A1 (0.44) | KMT2AGAAKDM4EALDH1A1MAPK1 | |
| SCHEMBL31185049 | 0.84 | ALDH1A1 (0.44) | KMT2AGAAKDM4EALDH1A1MAPK1 | |
| SCHEMBL31185026 | 0.82 | KMT2A (0.48) | KMT2AGAAMEN1EPHX2KDM4E | |
| SCHEMBL31184979 | 0.82 | ALDH1A1 (0.46) | KMT2AGAAMEN1KDM4EALDH1A1 | |
| SCHEMBL31184809 | 0.81 | MAPK1 (0.42) | KMT2AMEN1KDM4EALDH1A1MAPK1 | |
| SCHEMBL31184763 | 0.79 | EPHX2 (0.49) | KMT2AMEN1EPHX2ALDH1A1NPC1 | |
| SCHEMBL31184399 | 0.79 | ALDH1A1 (0.43) | KMT2AMEN1KDM4EALDH1A1NPC1 | |
| SCHEMBL31184422 | 0.79 | MAPK1 (0.40) | KMT2AGAAMEN1KDM4EALDH1A1 | |
| SCHEMBL31184529 | 0.78 | MAPK1 (0.49) | KMT2AMEN1MAPK1 | |
| SCHEMBL31184632 | 0.77 | MAPK1 (0.46) | KMT2AGAAMEN1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |