Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14867208 | 0.91 | P2RX7 (0.36) | CA1CA2POLBP2RX7MAPT | |
| SCHEMBL14234758 | 0.90 | F10 (0.35) | CA1CA2POLBSETDB1P2RX7 | |
| SCHEMBL12069085 | 0.89 | PTGES (0.36) | CA1CA2POLBP2RX7 | |
| SCHEMBL12069084 | 0.89 | BTK (0.37) | P2RX7BTK | |
| SCHEMBL12070340 | 0.89 | MIF (0.36) | CA1CA2P2RX7MAPTBTK | |
| SCHEMBL12070343 | 0.89 | P2RX7 (0.35) | CA1CA2POLBP2RX7MAPT | |
| SCHEMBL12069099 | 0.88 | SMN1; SMN2 (0.34) | CA1CA2P2RX7 | |
| SCHEMBL12070339 | 0.88 | EPHX2 (0.36) | P2RX7BTK | |
| SCHEMBL3123196 | 0.88 | PTGS2 (0.33) | CA1CA2POLBSETDB1F10 | |
| SCHEMBL12070342 | 0.87 | TP53 (0.35) | CA1CA2P2RX7MAPTBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9023836-B2 | Use of substituted heterocyclic compounds to control sea lice on fish | NOVARTIS TIERGESUNDHEIT AG (CH) | 2015-05-05 | — | — | US | disclosed |
| US-9023836-B2 | Use of substituted heterocyclic compounds to control sea lice on fish | NOVARTIS TIERGESUNDHEIT AG (CH) | 2015-05-05 | — | — | US | disclosed |
| CN-101652354-B | Insecticidal aryl isoxazoline derivatives | BAYER CROPSCIENCE AG | 2014-06-18 | — | — | CN | disclosed |
| US-20130095126-A1 | USE OF SUBSTITUTED HETEROCYCLIC COMPOUNDS TO CONTROL SEA LICE ON FISH | NOVARTIS TIERGESUNDHEIT AG (CH) | 2013-04-18 | — | — | US | disclosed |
| US-20130095126-A1 | USE OF SUBSTITUTED HETEROCYCLIC COMPOUNDS TO CONTROL SEA LICE ON FISH | NOVARTIS TIERGESUNDHEIT AG (CH) | 2013-04-18 | — | — | US | disclosed |
| US-8372867-B2 | Insecticidal aryl isoxazoline derivatives | BAYER CROPSCIENCE AG (DE) | 2013-02-12 | — | — | US | disclosed |
| US-8372867-B2 | Insecticidal aryl isoxazoline derivatives | BAYER CROPSCIENCE AG (DE) | 2013-02-12 | — | — | US | disclosed |
| WO-2011157733-A2 | NEW USE | NOVARTIS AG (CH) | 2011-12-22 | — | — | WO | disclosed |
| US-20100179194-A1 | INSECTICIDAL ARYL ISOXAZOLINE DERIVATIVES | BAYER CORPSCIENCE AG (DE) | 2010-07-15 | — | — | US | disclosed |
| US-20100179194-A1 | INSECTICIDAL ARYL ISOXAZOLINE DERIVATIVES | BAYER CORPSCIENCE AG (DE) | 2010-07-15 | — | — | US | disclosed |
| EP-2181100-A2 | INSECTICIDAL ARYL ISOXAZOLINE DERIVATIVES | Bayer CropScience AG (DE) | 2010-05-05 | — | — | EP | disclosed |
| WO-2008122375-A2 | INSECTICIDAL ARYL ISOXAZOLINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179194-A1 | INSECTICIDAL ARYL ISOXAZOLINE DERIVATIVES | CYP4X1, AADAC, CYP3A7 | CA1 4328/4885CA2 1990/4885POLB 4597/4885 |
| US-20130095126-A1 | USE OF SUBSTITUTED HETEROCYCLIC COMPOUNDS TO CONTROL SEA LICE ON FISH | TYR, NISCH, GYPA | CA1 311/4885CA2 31/4885POLB 4285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.