Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | UBE2M | P61081 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31185053 | 0.89 | TP53 (0.40) | KMT2ALMNAALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL31184767 | 0.88 | MALT1 (0.45) | ALDH1A1SMN1; SMN2MALT1HPGD | |
| SCHEMBL31184614 | 0.86 | ALDH1A1 (0.40) | TSHRKMT2ALMNAALDH1A1POLB | |
| SCHEMBL31184642 | 0.86 | ALDH1A1 (0.40) | ALDH1A1POLBSMN1; SMN2KDM4EHPGD | |
| SCHEMBL31184949 | 0.83 | ALDH1A1 (0.39) | KMT2ALMNAALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL31184812 | 0.82 | MGLL (0.48) | MGLLEPHX2TSHRKMT2ALMNA | |
| SCHEMBL31184615 | 0.82 | LMNA (0.31) | LMNAPOLB | |
| SCHEMBL31184824 | 0.82 | ALDH1A1 (0.37) | KMT2AALDH1A1POLBSMN1; SMN2MALT1 | |
| SCHEMBL31184568 | 0.81 | MAPK1 (0.32) | TSHRALDH1A1POLB | |
| SCHEMBL31184750 | 0.80 | BTK (0.34) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |