Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 3/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | CHKB | Q9Y259 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184614 | 0.94 | ALDH1A1 (0.40) | TP53ALDH1A1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL31184642 | 0.92 | ALDH1A1 (0.40) | TP53ALDH1A1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL31184767 | 0.92 | MALT1 (0.45) | ALDH1A1SMN1; SMN2HPGDMAPTACHE | |
| SCHEMBL31184949 | 0.91 | ALDH1A1 (0.39) | TP53ALDH1A1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL31184992 | 0.89 | MGLL (0.41) | ALDH1A1SMN1; SMN2HPGDPOLBKMT2A | |
| SCHEMBL31184824 | 0.88 | ALDH1A1 (0.37) | TP53ALDH1A1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL31184842 | 0.85 | HPGD (0.37) | TP53ALDH1A1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL31184468 | 0.83 | TP53 (0.44) | TP53ALDH1A1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL31184730 | 0.83 | ALDH1A1 (0.41) | TP53ALDH1A1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL31184750 | 0.83 | BTK (0.34) | ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |