Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12844405 | 0.80 | ACHE (0.50) | ACHEALDH1A1SMN1; SMN2ERN1CYP3A4 | |
| SCHEMBL31187890 | 0.78 | ACHE (0.48) | ACHEALDH1A1SMN1; SMN2ERN1 | |
| SCHEMBL5141831 | 0.78 | ACHE (0.48) | ACHEHPGDMAPK1POLBNPSR1 | |
| SCHEMBL13296654 | 0.77 | ALOX5 (0.54) | ACHEPOLB | |
| SCHEMBL13027473 | 0.75 | ACHE (0.45) | ACHEALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL28151678 | 0.75 | ALOX5 (0.46) | ACHEGABRA1GABRG2GABRB3MAPT | |
| SCHEMBL5141794 | 0.75 | ACHE (0.54) | ACHEALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL12776535 | 0.73 | ACHE (0.52) | ACHEALDH1A1SMN1; SMN2ERN1CYP3A4 | |
| SCHEMBL29140671 | 0.72 | ALDH1A1 (0.46) | ACHEALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL3606088 | 0.71 | POLB (0.48) | POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4683918-A1 | NLRP3 INFLAMMASOME INHIBITORS AND USES THEREOF | Insilico Medicine IP Limited (HK) | 2026-01-28 | — | — | EP | disclosed |
| WO-2024193541-A1 | NLRP3 INFLAMMASOME INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2024-09-26 | — | — | WO | disclosed |