Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.34 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.34 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19410144 | 1.00 | TPSAB1 (0.34) | TPSAB1TPSD1TPSG1L3MBTL1TSHR | |
| SCHEMBL19427093 | 0.89 | MAPT (0.31) | POLBMAPTXBP1NPSR1TDP1 | |
| SCHEMBL19410228 | 0.89 | MTNR1A (0.33) | TPSAB1TPSD1TPSG1L3MBTL1HTR6 | |
| SCHEMBL19410193 | 0.87 | L3MBTL1 (0.44) | TPSAB1TPSD1TPSG1L3MBTL1HTR6 | |
| SCHEMBL19410146 | 0.78 | SLC7A5 (0.38) | L3MBTL1MAPTHTR6MTNR1AMTNR1B | |
| SCHEMBL19410199 | 0.75 | PLK1 (0.46) | L3MBTL1MAPTMTNR1AMTNR1B | |
| SCHEMBL19410213 | 0.73 | ALDH1A1 (0.43) | TPSAB1TPSD1TPSG1L3MBTL1TSHR | |
| SCHEMBL19410194 | 0.71 | PLK1 (0.42) | L3MBTL1HTR6 | |
| SCHEMBL16284728 | 0.71 | SYK (0.50) | TPSAB1TPSD1TPSG1L3MBTL1RAB9A | |
| SCHEMBL19410169 | 0.70 | SLC16A3 (0.36) | TPSAB1TPSD1TPSG1NPSR1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3440097-B1 | MACROCYCLIC INHIBITORS OF THE PD-1/PD-L1 AND CD80/PD-L1 PROTEIN/PROTEIN INTERACTIONS | BRISTOL MYERS SQUIBB CO (US) | 2024-10-23 | — | — | EP | disclosed |