Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ1A | Q9NRL2 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3116059 | 0.81 | ROCK2 (0.67) | KMT2AMEN1POLBSMN1; SMN2GAA | |
| SCHEMBL11620122 | 0.77 | KMT2A (0.63) | BAZ1AKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL11846748 | 0.75 | PYCR1 (0.53) | BAZ1AKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL29566253 | 0.75 | CYP1A2 (0.58) | BAZ1AKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL11617516 | 0.74 | NAMPT (0.67) | BAZ1AKMT2AALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL13234645 | 0.74 | KMT2A (0.62) | BAZ1AKMT2AMEN1SMN1; SMN2PYCR1 | |
| SCHEMBL11614038 | 0.73 | ALDH1A1 (0.58) | BAZ1AKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL3441758 | 0.73 | PYCR1 (0.53) | BAZ1AKMT2AMEN1ALDH1A1POLB | |
| SCHEMBL27903466 | 0.72 | KMT2A (0.86) | KMT2AMEN1ALDH1A1POLBTHRA | |
| SCHEMBL11612243 | 0.72 | MTOR (0.54) | KMT2AMEN1ALDH1A1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036316-A1 | UREA AND CARBAMATE COMPOUNDS AND ANALOGS AS KINASE INHIBITORS | FENG YANGBO (US) | 2010-04-01 | — | — | WO | disclosed |