Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31292288 | 0.77 | MMP8 (0.41) | POLBCYP1A2L3MBTL1MAPTRAB9A | |
| SCHEMBL31190568 | 0.76 | MAOA (0.50) | POLBCYP1A2CYP3A4CYP2D6PRMT1 | |
| SCHEMBL29715410 | 0.74 | POLB (0.55) | POLBMAPTRAB9ACA12CA1 | |
| SCHEMBL23092860 | 0.74 | POLB (0.55) | POLBMAPTRAB9ACA12CA1 | |
| SCHEMBL15560521 | 0.74 | POLB (0.46) | POLBL3MBTL1EGFRPTPRCRAB9A | |
| SCHEMBL22492226 | 0.74 | ALDH1A1 (0.49) | POLBCYP1A2CYP3A4CYP2D6L3MBTL1 | |
| SCHEMBL28023477 | 0.73 | POLB (0.61) | POLBL3MBTL1EGFRPTPRCMAPT | |
| SCHEMBL20063730 | 0.72 | POLB (0.43) | POLBCYP1A2CYP3A4CYP2D6PRMT1 | |
| SCHEMBL31190735 | 0.72 | KMT2A (0.46) | POLBCYP1A2CYP3A4CYP2D6L3MBTL1 | |
| SCHEMBL3126876 | 0.71 | MRGPRX4 (0.51) | POLBCYP1A2L3MBTL1PTPRCRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220747-A2 | FLUORINATED CYCLIC DERIVATIVES OF SULFONAMIDES AND SULFONES, AND COMPOSITIONS AND METHODS THEREOF | Lysoway Therapeutics, Inc. (US) | 2024-10-24 | — | — | WO | disclosed |