Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 4/20 | 0.40 |
| ▸ | EGFR | P00533 | 3/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.40 |
| ▸ | ABL1 | P00519 | 3/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | HCK | P08631 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.40 |
| ▸ | PRKDC | P78527 | 2/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3108981 | 0.74 | EGFR (0.53) | EGFRCSF1R | |
| SCHEMBL3124098 | 0.73 | XDH (0.53) | SRCPIK3CDKDRPIK3CAPIK3CB | |
| SCHEMBL17665421 | 0.70 | CSF1R (0.62) | CSF1R | |
| SCHEMBL17665719 | 0.69 | CSF1R (0.63) | CSF1R | |
| SCHEMBL5796557 | 0.65 | LMNA (0.45) | ALDH1A1TDP1 | |
| SCHEMBL2006792 | 0.63 | ALDH1A1 (0.52) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL4404667 | 0.62 | ABHD16A (0.59) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL22323697 | 0.62 | ALDH1A1 (0.50) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL23917259 | 0.62 | EGFR (0.46) | SRCEGFRPI4KBABL1PIK3CD | |
| SCHEMBL9153328 | 0.62 | HTT (0.56) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829570-B2 | Substituted 4-amino isoxazolo[5,4-d]pyrimidines as kinase inhibitors | ABBOTT LABORATORIES (US) | 2010-11-09 | — | — | US | disclosed |
| US-20100041676-A1 | Kinase inhibitors | ABBVIE INC. | 2010-02-18 | — | — | US | disclosed |
| US-20030225098-A1 | Kinase inhibitors | ABBOTT LABORATORIES | 2003-12-04 | — | — | US | disclosed |
| US-20030199525-A1 | Kinase inhibitors | ABBOTT LABORATORIES | 2003-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199525-A1 | Kinase inhibitors | MAP3K19, MAP3K9, MAP3K1 | SRC 173/4885EGFR 346/4885PI4KB 79/4885 |
| US-20030225098-A1 | Kinase inhibitors | MAP3K19, MAP3K9, MAP3K1 | SRC 242/4885EGFR 298/4885PI4KB 68/4885 |
| US-20100041676-A1 | Kinase inhibitors | MAP3K19, MAP3K20, MAP3K6 | SRC 51/4885EGFR 232/4885PI4KB 102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.