Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.31 |
| ▸ | SLC9A5 | Q14940 | 1/20 | 0.31 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24440189 | 0.84 | P2RX7 (0.35) | NOTUMNPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL24440171 | 0.82 | MAPK1 (0.33) | MAPK1SLC9A1SLC9A5SLC9A2 | |
| SCHEMBL27188251 | 0.80 | PTGS1 (0.37) | MAPK1SLC9A1SLC9A5SLC9A2 | |
| SCHEMBL1987212 | 0.75 | HSD17B3 (0.36) | MAPK1 | |
| SCHEMBL17193997 | 0.67 | MAOB (0.37) | HCAR3HCAR2ALDH1A1PKM | |
| SCHEMBL24440160 | 0.65 | KMT2A (0.43) | NOTUMTP53ALDH1A1CXCR5 | |
| SCHEMBL24440185 | 0.65 | LMNA (0.37) | NPC1RAB9AALDH1A1MAPK1PKM | |
| SCHEMBL1988784 | 0.65 | MAPK1 (0.44) | NOTUMNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL27188582 | 0.63 | ALDH1A1 (0.36) | RAB9ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL18469486 | 0.63 | CCR8 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4703358-A1 | BENZO SIX-MEMBERED HETEROCYCLIC GSPT1 PROTEIN DEGRADATION AGENT AND USE THEREOF | China Pharmaceutical University (CN) | 2026-03-04 | — | — | EP | disclosed |
| WO-2024222918-A1 | BENZO SIX-MEMBERED HETEROCYCLIC GSPT1 PROTEIN DEGRADATION AGENT AND USE THEREOF | 中国药科大学 | 2024-10-31 | — | — | WO | disclosed |