Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.31 |
| ▸ | SLC9A5 | Q14940 | 1/20 | 0.31 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24440189 | 0.84 | P2RX7 (0.35) | MAPK1SLC9A1SLC9A5SLC9A2 | |
| SCHEMBL31192059 | 0.82 | HCAR3 (0.35) | MAPK1SLC9A1SLC9A5SLC9A2 | |
| SCHEMBL27188251 | 0.80 | PTGS1 (0.37) | MAPK1SLC9A1SLC9A5SLC9A2 | |
| SCHEMBL1987212 | 0.75 | HSD17B3 (0.36) | MAPK1LTA4H | |
| SCHEMBL1988784 | 0.65 | MAPK1 (0.44) | MAPK1 | |
| SCHEMBL24440185 | 0.65 | LMNA (0.37) | MAPK1 | |
| SCHEMBL27188582 | 0.63 | ALDH1A1 (0.36) | MAPK1 | |
| SCHEMBL24440160 | 0.62 | KMT2A (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL3603114 | 0.62 | NPC1 (0.35) | MAPK1 | |
| SCHEMBL1986826 | 0.62 | ALOX15 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022103752-A1 | RAPID CONSTRUCTION OF TETRALIN, CHROMANE, AND INDANE MOTIFS VIA CYCLATIVE C-H/C-H COUPLING | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-05-19 | — | — | WO | disclosed |