Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.71 |
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.69 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.57 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.57 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | RXRA | P19793 | 5/20 | 0.54 |
| ▸ | RXRB | P28702 | 4/20 | 0.54 |
| ▸ | RXRG | P48443 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | XBP1 | P17861 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5605127 | 1.00 | PTGER1 (0.71) | PTGER1MRGPRX4NR4A2NR4A1NR4A3 | |
| SCHEMBL229472 | 0.88 | MRGPRX4 (0.69) | PTGER1MRGPRX4NR4A2NR4A1NR4A3 | |
| SCHEMBL3159761 | 0.87 | KMT2A (0.57) | PTGER1MRGPRX4KMT2AHPGDNPC1 | |
| SCHEMBL3721195 | 0.85 | HPGD (0.58) | PTGER1MRGPRX4MEN1KMT2ARXRA | |
| SCHEMBL29556736 | 0.85 | MRGPRX4 (0.62) | PTGER1MRGPRX4NR4A2NR4A1NR4A3 | |
| SCHEMBL1600077 | 0.85 | MRGPRX4 (0.62) | PTGER1MRGPRX4NR4A2NR4A1NR4A3 | |
| SCHEMBL6845399 | 0.85 | MRGPRX4 (0.55) | PTGER1MRGPRX4 | |
| Hydrochloric Acid SCHEMBL10857748 | 0.84 | MRGPRX4 (0.61) | PTGER1MRGPRX4NR4A2NR4A1NR4A3 | |
| SCHEMBL5100155 | 0.83 | PTGER1 (1.00) | PTGER1MRGPRX4RXRARXRBRXRG | |
| SCHEMBL25337360 | 0.83 | MRGPRX4 (0.59) | PTGER1MRGPRX4NR4A2NR4A1NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250214974-A1 | INHIBITING MONOACYLGLYCEROL LIPASE (MAGL) | PSY THERAPEUTICS, INC. (US) | 2025-07-03 | — | — | US | disclosed |
| US-12286421-B2 | Inhibiting monoacylglycerol lipase (MAGL) | PSY THERAPEUTICS, INC. (US) | 2025-04-29 | — | — | US | disclosed |
| US-20250084065-A1 | INHIBITING MONOACYLGLYCEROL LIPASE (MAGL) | PSY THERAPEUTICS, INC. (US) | 2025-03-13 | — | — | US | disclosed |
| US-20240308985-A1 | INHIBITING MONOACYLGLYCEROL LIPASE (MAGL) | PSY THERAPEUTICS, INC. (US) | 2024-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250214974-A1 | INHIBITING MONOACYLGLYCEROL LIPASE (MAGL) | MGLL, PNLIP, LIPC | PTGER1 4023/4885MRGPRX4 1186/4885NR4A2 4573/4885 |
| US-20250084065-A1 | INHIBITING MONOACYLGLYCEROL LIPASE (MAGL) | MGLL, PNLIP, LPL | PTGER1 2238/4885MRGPRX4 917/4885NR4A2 2851/4885 |
| US-12286421-B2 | Inhibiting monoacylglycerol lipase (MAGL) | MGLL, PNLIP, LIPC | PTGER1 4023/4885MRGPRX4 1186/4885NR4A2 4573/4885 |
| US-20240308985-A1 | INHIBITING MONOACYLGLYCEROL LIPASE (MAGL) | MGLL, PNLIP, LIPC | PTGER1 4023/4885MRGPRX4 1186/4885NR4A2 4573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.