Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31218918 | 0.87 | CHRM2 (0.47) | HPGDEPHX1HSD17B10OPRK1LMNA | |
| SCHEMBL30627206 | 0.86 | HPGD (0.42) | HPGDEPHX1HSD17B10OPRK1LMNA | |
| SCHEMBL28100905 | 0.83 | HPGD (0.49) | HPGDEPHX1HSD17B10PREPSMN1; SMN2 | |
| SCHEMBL28516773 | 0.83 | HPGD (0.49) | HPGDEPHX1HSD17B10PREPSMN1; SMN2 | |
| SCHEMBL5246013 | 0.80 | HSD17B10 (0.47) | HPGDEPHX1HSD17B10PREPSMN1; SMN2 | |
| SCHEMBL26603927 | 0.80 | HPGD (0.47) | HPGDEPHX1HSD17B10PREPSMN1; SMN2 | |
| SCHEMBL27720507 | 0.80 | HPGD (0.47) | HPGDEPHX1HSD17B10PREPSMN1; SMN2 | |
| SCHEMBL10782598 | 0.80 | HSD17B10 (0.47) | HPGDEPHX1HSD17B10PREPSMN1; SMN2 | |
| SCHEMBL15221624 | 0.79 | HPGD (0.46) | HPGDEPHX1HSD17B10PREPSMN1; SMN2 | |
| SCHEMBL16352852 | 0.79 | HPGD (0.46) | HPGDEPHX1HSD17B10PREPSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118574827-A | BRM targeting compounds and related methods of use | 阿维纳斯运营公司 | 2024-08-30 | — | — | CN | disclosed |