Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26117053 | 1.00 | NPC1 (0.42) | NPC1RAB9ASNCAALDH1A1CYP3A4 | |
| SCHEMBL4521109 | 0.87 | ALDH1A1 (0.43) | NPC1RAB9ASNCAALDH1A1CYP3A4 | |
| SCHEMBL5477046 | 0.82 | LPL (0.35) | TYRCA1CA2CA9 | |
| SCHEMBL28961843 | 0.81 | CXCR2 (0.42) | UCHL1CA1CA2CA9HIF1A | |
| SCHEMBL31114631 | 0.81 | CXCR2 (0.42) | UCHL1CA1CA2CA9HIF1A | |
| SCHEMBL31034978 | 0.81 | CA1 (0.36) | ALDH1A1UCHL1CA1CA2CA9 | |
| SCHEMBL5899720 | 0.81 | CA2 (0.47) | SNCAALDH1A1CYP3A4HPGDUCHL1 | |
| SCHEMBL7162404 | 0.81 | SNCA (0.42) | SNCAALDH1A1CYP3A4HPGDUCHL1 | |
| SCHEMBL29424578 | 0.81 | CA2 (0.47) | SNCAALDH1A1CYP3A4HPGDUCHL1 | |
| SCHEMBL16553305 | 0.80 | SNCA (0.41) | NPC1RAB9ASNCAALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680601-A1 | PYRIDAZINE COMPOUNDS, THEIR PREPARATION, AND THEIR THERAPEUTIC USES | Sanofi (FR) | 2026-01-21 | — | — | EP | disclosed |
| WO-2024188994-A1 | PYRIDAZINE COMPOUNDS, THEIR PREPARATION, AND THEIR THERAPEUTIC USES | SANOFI (FR) | 2024-09-19 | — | — | WO | disclosed |