Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 8/20 | 0.39 |
| ▸ | JAK1 | P23458 | 7/20 | 0.39 |
| ▸ | TYK2 | P29597 | 5/20 | 0.39 |
| ▸ | JAK3 | P52333 | 4/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | WNT1 | P04628 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CLK3 | P49761 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | KHK | P50053 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31204072 | 0.92 | JAK2 (0.34) | JAK2JAK1TYK2JAK3DGAT1 | |
| SCHEMBL31204112 | 0.78 | PIK3CG (0.41) | JAK2JAK1TYK2JAK3RIPK1 | |
| SCHEMBL31204341 | 0.74 | WNT3A (0.37) | WNT1GSK3BDYRK1ACLK2CLK3 | |
| SCHEMBL31204259 | 0.68 | MAP3K5 (0.53) | WNT1GSK3BDYRK1ACLK2CLK3 | |
| SCHEMBL31204118 | 0.68 | DYRK1A (0.33) | WNT1GSK3BDYRK1ACLK2CLK3 | |
| SCHEMBL31204203 | 0.64 | OTUD7B (0.47) | WNT1GSK3BDYRK1AOTUD7BPIK3CG | |
| SCHEMBL31204270 | 0.62 | MAP3K5 (0.48) | DYRK1AABL1OTUD7BPIK3CG | |
| SCHEMBL30132037 | 0.60 | NPC1 (0.36) | — | |
| SCHEMBL31204151 | 0.59 | MAP3K5 (0.47) | DYRK1AABL1OTUD7BPIK3CG | |
| SCHEMBL31204048 | 0.57 | DAGLA (0.37) | DYRK1AABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727938-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS FOR TREATING NEUROLOGICAL DISORDERS | Prothena Biosciences Limited (IE) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024259121-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2024-12-19 | — | — | WO | disclosed |