Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 12/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | TTK | P33981 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 2/20 | 0.41 |
| ▸ | WNT1 | P04628 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31204112 | 0.74 | PIK3CG (0.41) | PIK3CGPIK3CAPIK3CDPIK3CB | |
| SCHEMBL3087482 | 0.71 | PIK3CG (0.63) | PIK3CGPIK3CAPIK3CDPIK3CB | |
| SCHEMBL13031379 | 0.66 | JAK1 (0.67) | GSK3B | |
| SCHEMBL3093859 | 0.65 | PIK3CG (0.72) | PIK3CGPIK3CAPIK3CDPIK3CB | |
| SCHEMBL3081270 | 0.64 | PIK3CG (0.68) | PIK3CGPIK3CAPIK3CDPIK3CB | |
| SCHEMBL29757180 | 0.64 | NPC1 (1.00) | PIK3CAPIK3CDGSK3BNPC1POLB | |
| SCHEMBL30743 | 0.64 | NPC1 (1.00) | PIK3CAPIK3CDGSK3BNPC1POLB | |
| SCHEMBL31204329 | 0.64 | GSK3B (0.52) | GSK3BWNT1DYRK1A | |
| SCHEMBL31204341 | 0.64 | WNT3A (0.37) | GSK3BWNT1DYRK1A | |
| SCHEMBL19031312 | 0.64 | OTUD7B (1.00) | OTUD7BNPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727938-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS FOR TREATING NEUROLOGICAL DISORDERS | Prothena Biosciences Limited (IE) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024259121-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2024-12-19 | — | — | WO | disclosed |