Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 12/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.37 |
| ▸ | WNT1 | P04628 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | CLK3 | P49761 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31204118 | 0.79 | DYRK1A (0.33) | DYRK1AWNT1GSK3BCLK2CLK3 | |
| SCHEMBL31204286 | 0.74 | OTUD7B (0.49) | DYRK1AWNT1GSK3BCLK2CLK3 | |
| SCHEMBL31204146 | 0.74 | JAK2 (0.39) | DYRK1AWNT1GSK3BCLK2CLK3 | |
| SCHEMBL31204077 | 0.69 | OTUD7B (0.45) | DYRK1AWNT1GSK3BCLK2ABL1 | |
| SCHEMBL31204072 | 0.68 | JAK2 (0.34) | — | |
| SCHEMBL31204132 | 0.66 | OTUD7B (0.45) | CLK2ABL1 | |
| SCHEMBL31204112 | 0.64 | PIK3CG (0.41) | — | |
| SCHEMBL31204203 | 0.64 | OTUD7B (0.47) | DYRK1AWNT1GSK3B | |
| SCHEMBL31204064 | 0.61 | OTUD7B (0.46) | DYRK1AWNT1GSK3BCLK2CLK3 | |
| SCHEMBL16812907 | 0.61 | CFTR (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727938-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS FOR TREATING NEUROLOGICAL DISORDERS | Prothena Biosciences Limited (IE) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024259121-A1 | BICYCLIC HETEROAROMATIC COMPOUNDS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2024-12-19 | — | — | WO | disclosed |