Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.55 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30279129 | 0.79 | NISCH (0.47) | TRPV1RXRARXRBRXRGALDH1A1 | |
| SCHEMBL25042203 | 0.79 | NISCH (0.47) | TRPV1RXRARXRBRXRGALDH1A1 | |
| SCHEMBL29218778 | 0.79 | TRPV1 (0.46) | TRPV1RXRARXRBRXRGALDH1A1 | |
| SCHEMBL9226612 | 0.77 | KDM4E (0.51) | ALDH1A1MEN1KMT2ALMNATHRA | |
| SCHEMBL19305874 | 0.77 | ALDH1A1 (0.60) | TRPV1RXRARXRBRXRGALDH1A1 | |
| SCHEMBL15574631 | 0.74 | NPC1 (0.44) | ALDH1A1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL6627142 | 0.73 | ALDH1A1 (0.65) | RXRARXRBRXRGALDH1A1MEN1 | |
| SCHEMBL3125795 | 0.73 | SIGMAR1 (0.48) | ALDH1A1MEN1KMT2ALMNATHRA | |
| SCHEMBL4941675 | 0.73 | KDM4E (0.60) | MEN1KMT2AKDM4EHDAC6 | |
| SCHEMBL4941681 | 0.73 | KDM4E (0.60) | MEN1KMT2AKDM4EHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240360114-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2024-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240360114-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | AIFM2, GPX1, GPX4 | TRPV1 3530/4885RXRA 674/4885RXRB 502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.