Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31207449 | 0.83 | SCN9A (0.43) | ACACBACACASCN9AFFAR4PTGS1 | |
| SCHEMBL31207397 | 0.81 | FFAR4 (0.40) | SCN9AFFAR4KDM1AKDM1B | |
| SCHEMBL31207389 | 0.81 | SCN9A (0.46) | ACACBACACASCN9A | |
| SCHEMBL31207382 | 0.79 | EPHX2 (0.39) | SCN9A | |
| SCHEMBL31207401 | 0.79 | GRM5 (0.38) | — | |
| SCHEMBL15536664 | 0.73 | SCN9A (0.54) | SCN9AKDM1AKDM1B | |
| SCHEMBL363646 | 0.69 | SCN9A (0.51) | SCN9AHTR2ASLC6A4 | |
| SCHEMBL1547720 | 0.68 | CHRNA3 (0.49) | CHRM4 | |
| SCHEMBL31207456 | 0.68 | RXRA (0.40) | KDM1AKDM1B | |
| SCHEMBL31207421 | 0.68 | NR4A2 (0.40) | SCN9AFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4702021-A1 | COMPOUNDS CAPABLE OF MODULATING GPR65 | Pathios Therapeutics Limited (GB) | 2026-03-04 | — | — | EP | disclosed |
| WO-2024224064-A1 | COMPOUNDS CAPABLE OF MODULATING GPR65 | Pathios Therapeutics Limited (GB) | 2024-10-31 | — | — | WO | disclosed |