Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.51 |
| ▸ | NPC1 | O15118 | 8/20 | 0.51 |
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | HPGD | P15428 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | FBP1 | P09467 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1748058 | 1.00 | KDM4E (0.51) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL1748081 | 0.86 | KDM4E (0.53) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL18613864 | 0.81 | FBP1 (0.44) | KDM4ENPC1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL31208321 | 0.81 | FBP1 (0.44) | ALDH1A1SMN1; SMN2POLBMAPTFBP1 | |
| SCHEMBL1748273 | 0.81 | FBP1 (0.44) | ALDH1A1SMN1; SMN2POLBMAPTFBP1 | |
| SCHEMBL1748135 | 0.79 | MAPT (0.51) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL1748015 | 0.79 | SMN1; SMN2 (0.37) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL305334 | 0.77 | LMNA (0.53) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL1747969 | 0.76 | GAA (0.42) | KDM4ENPC1RAB9AALDH1A1HPGD | |
| SCHEMBL128635 | 0.76 | FBP1 (0.61) | KDM4ENPC1RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113874074-B | HMOX1 inducers | 米托布里奇公司 | 2024-11-01 | — | — | CN | disclosed |