Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formamide SCHEMBL9380540 | 0.92 | LMNA (0.47) | LMNAGAAALOX15TDP1PTGS2 | |
| SCHEMBL329398 | 0.86 | MAPT (0.47) | LMNAGAAALOX15TDP1PTGS2 | |
| SCHEMBL2244849 | 0.81 | LMNA (0.50) | LMNAGAAALOX15TDP1PTGS2 | |
| SCHEMBL3136339 | 0.81 | MAPT (0.46) | LMNAGAAALOX15TDP1PTGS2 | |
| SCHEMBL31665885 | 0.81 | MAPT (0.46) | LMNAGAAALOX15TDP1PTGS2 | |
| SCHEMBL329399 | 0.81 | MAPT (0.46) | LMNAGAAALOX15TDP1PTGS2 | |
| SCHEMBL544259 | 0.81 | MAPT (0.46) | LMNAGAAALOX15TDP1PTGS2 | |
| SCHEMBL15157903 | 0.80 | MAPT (0.46) | LMNAGAAALOX15TDP1PTGS2 | |
| SCHEMBL14862829 | 0.80 | MAPT (0.47) | LMNAGAAALOX15TDP1PTGS2 | |
| SCHEMBL8232118 | 0.77 | MAPT (0.47) | LMNAGAAALOX15TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240409533-A1 | HMOX1 INDUCERS | Astellas Engineered Small Molecules US, Incorporated | 2024-12-12 | — | — | US | disclosed |
| CN-113874074-B | HMOX1 inducers | 米托布里奇公司 | 2024-11-01 | — | — | CN | disclosed |
| US-12071433-B2 | HMOX1 inducers | Astellas Engineered Small Molecules US, Incorporated (US) | 2024-08-27 | — | — | US | disclosed |
| US-20240051952-A1 | HMOX1 INDUCERS | Astellas Engineered Small Molecules US, Incorporated | 2024-02-15 | — | — | US | disclosed |
| CN-115925651-B | Photochemical synthesis method of benzoxazole-2-alkyl alcohol | 合肥工业大学 | 2023-12-05 | — | — | CN | disclosed |
| CN-115666656-A | Bilateral functionalization of antibodies by cycloaddition | 西纳福克斯股份有限公司 | 2023-01-31 | — | — | CN | disclosed |
| US-20220177460-A1 | HMOX1 INDUCERS | Astellas Engineered Small Molecules US, Incorporated | 2022-06-09 | — | — | US | disclosed |
| US-11332779-B2 | Nucleic acid melting analysis with saturation dyes | BIOFIRE DEFENSE, LLC (US) | 2022-05-17 | — | — | US | disclosed |
| EP-3952990-A1 | HMOX1 INDUCERS | Mitobridge, Inc. (US) | 2022-02-16 | — | — | EP | disclosed |
| CN-113874074-A | HMOX1 inducers | 米托布里奇公司 | 2021-12-31 | — | — | CN | disclosed |
| US-7091228-B2 | Preparation and use of aryl alkyl acid derivatives for the treatment of obesity | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-08-15 | — | — | US | disclosed |
| EP-1633722-A2 | PREPARATION AND USE OF ARYL ALKYL ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | Bayer Pharmaceuticals Corporation (US) | 2006-03-15 | — | — | EP | disclosed |
| US-20060019253-A1 | Polymerase chain reaction analysis by mixing a dsDNA binding dye with a sample of target nucleic acid and primers configured for amplifying; melting the amplified target nucleic acid to generate a melting curve; plotting; repeating; comparison; melting curve difference for each target nucleic acid | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-01-26 | — | — | US | disclosed |
| US-20050233335-A1 | standard PCR solution with additional saturating double-stranded (ds) DNA binding dye; fluorescence; cyanine dyes | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2005-10-20 | — | — | US | disclosed |
| EP-1558762-A2 | AMPLICON MELTING ANALYSIS WITH SATURATION DYES | University of Utah Research Foundation (US) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004100881-A2 | PREPARATION AND USE OF ARYL ALKYL ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-11-25 | — | — | WO | disclosed |
| US-20040224997-A1 | Preparation and use of aryl alkyl acid derivatives for the treatment of obesity | BAYER PHARMACEUTICALS CORPORATION | 2004-11-11 | — | — | US | disclosed |
| WO-2004038038-A2 | AMPLICON MELTING ANALYSIS WITH SATURATION DYES | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2004-05-06 | — | — | WO | disclosed |
| US-5364875-A | Anticholesterol agents | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-11-15 | — | — | US | disclosed |
| WO-1993023392-A1 | IMIDAZOLES LINKED TO BICYCLIC HETEROCYCLIC GROUPS FOR THE TREATMENT OF ATHEROSCLEROSIS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040224997-A1 | Preparation and use of aryl alkyl acid derivatives for the treatment of obesity | FABP4, GPR119, LIPC | LMNA 844/4885GAA 307/4885ALOX15 118/4885 |
| US-20060019253-A1 | Polymerase chain reaction analysis by mixing a dsDNA binding dye with a sample of target nucleic acid and primers configured for amplifying; melting the amplified target nucleic acid to generate a melting curve; plotting; repeating; comparison; melting curve difference for each target nucleic acid | POLL, DNA2, POLRMT | LMNA 283/4885GAA 1399/4885ALOX15 3829/4885 |
| US-20240409533-A1 | HMOX1 INDUCERS | HMOX1, HMOX2, HMBS | LMNA 3346/4885GAA 2202/4885ALOX15 14/4885 |
| US-12071433-B2 | HMOX1 inducers | HMOX1, HMOX2, HMBS | LMNA 3437/4885GAA 2123/4885ALOX15 13/4885 |
| US-20240051952-A1 | HMOX1 INDUCERS | HMOX1, HMOX2, QSOX1 | LMNA 1942/4885GAA 1965/4885ALOX15 11/4885 |
| US-20050233335-A1 | standard PCR solution with additional saturating double-stranded (ds) DNA binding dye; fluorescence; cyanine dyes | DDB1, POLL, POLRMT | LMNA 258/4885GAA 2431/4885ALOX15 4753/4885 |
| US-20220177460-A1 | HMOX1 INDUCERS | HMOX1, HMOX2, HMBS | LMNA 3437/4885GAA 2123/4885ALOX15 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.