Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 6/20 | 0.51 |
| ▸ | TLR2 | O60603 | 4/20 | 0.49 |
| ▸ | MDM4 | O15151 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31212513 | 1.00 | MDM2 (0.51) | MDM2TLR2MDM4TP53PTPN1 | |
| SCHEMBL2288397 | 0.93 | MDM2 (0.57) | MDM2TLR2MDM4TP53KMT2A | |
| SCHEMBL436024 | 0.93 | MDM2 (0.57) | MDM2TLR2MDM4TP53KMT2A | |
| SCHEMBL29362301 | 0.93 | MDM2 (0.57) | MDM2TLR2MDM4TP53KMT2A | |
| SCHEMBL29792115 | 0.93 | MDM2 (0.57) | MDM2TLR2MDM4TP53KMT2A | |
| SCHEMBL31681399 | 0.93 | MDM2 (0.57) | MDM2TLR2MDM4TP53KMT2A | |
| SCHEMBL6158363 | 0.93 | MDM2 (0.57) | MDM2TLR2MDM4TP53KMT2A | |
| SCHEMBL29547181 | 0.93 | MDM2 (0.57) | MDM2TLR2MDM4TP53KMT2A | |
| SCHEMBL31677955 | 0.91 | MDM2 (0.51) | MDM2MDM4TP53PTPN1 | |
| SCHEMBL21192401 | 0.90 | MDM2 (0.58) | MDM2TLR2MDM4TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3027228-B1 | MODULAR IMAGING AGENTS CONTAINING AMINO ACIDS AND PEPTIDES | ROCHESTER INSTITUTE TECH (US) | 2024-10-02 | — | — | EP | disclosed |