Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 3/20 | 0.31 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 2/20 | 0.30 |
| ▸ | HTR2A | P28223 | 2/20 | 0.30 |
| ▸ | HTR2C | P28335 | 2/20 | 0.30 |
| ▸ | HTR2B | P41595 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17541475 | 0.82 | TUBB4A (0.34) | P2RX3P2RX2HTR1AHTR2AHTR2C | |
| SCHEMBL21823272 | 0.81 | HTR1A (0.41) | P2RX3P2RX2HTR1AHTR2AHTR2C | |
| SCHEMBL29694847 | 0.81 | HTR1A (0.41) | P2RX3P2RX2HTR1AHTR2AHTR2C | |
| SCHEMBL31281220 | 0.79 | NPC1 (0.31) | XDH | |
| SCHEMBL389291 | 0.79 | NPC1 (0.31) | XDH | |
| SCHEMBL594407 | 0.79 | XDH (0.30) | XDH | |
| SCHEMBL31519323 | 0.79 | BACE1 (0.33) | EGFRERBB2XDH | |
| SCHEMBL29965599 | 0.79 | XDH (0.30) | XDH | |
| SCHEMBL20271260 | 0.79 | BACE1 (0.33) | EGFRERBB2XDH | |
| SCHEMBL12036983 | 0.76 | EGFR (0.32) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024238406-A1 | FUROPYRIDINE COMPOUNDS AS P53 MUTANT STABILIZER AND USES THEREOF | FRONTIER MEDICINES CORPORATION (US) | 2024-11-21 | — | — | WO | disclosed |