Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.42 |
| ▸ | OGA | O60502 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26101178 | 1.00 | RAB9A (0.54) | RAB9AMAPTNPC1KMT2AMAPK1 | |
| SCHEMBL16794688 | 0.86 | P2RY12 (0.46) | RAB9AMAPTNPC1KDM4ETSHR | |
| SCHEMBL26101531 | 0.81 | GAA (0.46) | RAB9AMAPTNPC1KDM4EL3MBTL1 | |
| SCHEMBL31218818 | 0.80 | RAB9A (0.61) | RAB9AMAPTNPC1KMT2AMAPK1 | |
| SCHEMBL20689381 | 0.79 | TYK2 (0.40) | RAB9AMAPTNPC1KMT2AALDH1A1 | |
| SCHEMBL20689682 | 0.78 | ALDH1A1 (0.48) | KDM4EPOLBALDH1A1HSD17B10HPGD | |
| SCHEMBL20689137 | 0.78 | ALDH1A1 (0.51) | KDM4EL3MBTL1POLBALDH1A1HSD17B10 | |
| SCHEMBL23753623 | 0.76 | NOS3 (0.39) | RAB9ANPC1KMT2ATSHRALDH1A1 | |
| SCHEMBL18161077 | 0.76 | GPR119 (0.34) | RAB9ANPC1KDM4EL3MBTL1HRH3 | |
| SCHEMBL31572570 | 0.74 | TYK2 (0.32) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119013277-A | TYK2 degrading agent and application thereof | 凯麦拉医疗公司 | 2024-11-22 | — | — | CN | disclosed |