Etofibrate

Etofibrate

SCHEMBL3122

CC(C)(Oc1ccc(Cl)cc1)C(=O)OCCOC(=O)c1cccnc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.55
KMT2A Q03164 6/20 0.55
LMNA P02545 5/20 0.55
ALDH1A1 P00352 4/20 0.55
MEN1 O00255 2/20 0.55
USP2 O75604 1/20 0.55
CYP1A2 P05177 3/20 0.54
CYP3A4 P08684 2/20 0.54
TSHR P16473 2/20 0.54
ABCB11 O95342 1/20 0.54
HTR2A P28223 1/20 0.54
PMP22 Q01453 1/20 0.54
PPARA Q07869 1/20 0.54
CYP2C9 P11712 2/20 0.54
CYP2C19 P33261 2/20 0.54
SMN1; SMN2 Q16637 1/20 0.52
MAPT P10636 2/20 0.48
HPGD P15428 1/20 0.48
KDM4E B2RXH2 1/20 0.47
THRB P10828 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Etofibrate SCHEMBL8168409 1.00 L3MBTL1 (0.55) L3MBTL1KMT2ALMNAALDH1A1MEN1
Etofibrate SCHEMBL29801484 1.00 L3MBTL1 (0.55) L3MBTL1KMT2ALMNAALDH1A1MEN1
Etofibrate SCHEMBL1649349 0.99 L3MBTL1 (0.54) L3MBTL1KMT2ALMNAALDH1A1MEN1
Ronifibrate SCHEMBL48852 0.96 L3MBTL1 (0.59) L3MBTL1KMT2ALMNAALDH1A1MEN1
Simfibrate SCHEMBL5808862 0.96 L3MBTL1 (0.59) L3MBTL1KMT2ALMNAALDH1A1MEN1
SCHEMBL10973734 0.92 L3MBTL1 (0.55) L3MBTL1KMT2ALMNAALDH1A1MEN1
Picafibrate SCHEMBL2109083 0.85 SMN1; SMN2 (0.65) KMT2ALMNAALDH1A1MEN1USP2
Binifibrate SCHEMBL49116 0.85 KMT2A (0.51) L3MBTL1KMT2ALMNAALDH1A1MEN1
Binifibrate SCHEMBL29388376 0.85 KMT2A (0.51) L3MBTL1KMT2ALMNAALDH1A1MEN1
SCHEMBL2615470 0.84 L3MBTL1 (0.59) L3MBTL1KMT2ALMNAALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5654 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
US-20240398789-A1 PHARMACEUTICAL COMPOSITION FOR ENHANCING ANTI-TUMOR EFFECT OF EZH2 INHIBITOR AND USE THEREOF PEKING UNIVERSITY THIRD HOSPITAL (CN) 2024-12-05 US claimed
CN-118236501-A A composition containing PPARα agonist and folic acid substances 深圳奥萨医药有限公司 2024-06-25 CN claimed
CN-116568802-A In vitro method for preparing mature red blood cells 西湖生物医药科技(上海)有限公司 2023-08-08 CN claimed
WO-2023061446-A1 PHARMACEUTICAL COMPOSITION FOR ENHANCING ANTI-TUMOR EFFECT OF EZH2 INHIBITOR, AND USE THEREOF 北京大学第三医院(北京大学第三临床医学院) 2023-04-20 WO claimed
EP-4165233-A1 HYBRID ELECTRODIALYSIS AND ELECTROLYSIS SYSTEMS AND PROCESSES Pani Clean, Inc. (US) 2023-04-19 EP claimed
US-20230059619-A1 SOLID DISPERSIONS INTERNATIONAL N&H USA, INC. 2023-02-23 US claimed
CN-115364231-A Pharmaceutical composition for enhancing anti-tumor effect of EZH2 inhibitor and application thereof 北京大学第三医院(北京大学第三临床医学院) 2022-11-22 CN claimed
US-11504324-B2 Nanosuspension formulation DuPont Nutrition USA, Inc. (US) 2022-11-22 US claimed
US-11369575-B2 PPARα agonist compositions and methods of use THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) 2022-06-28 US claimed
WO-1997037629-A1 PROCESS FOR ENCAPSULATION OF CAPLETS IN A CAPSULE AND SOLID DOSAGE FORMS OBTAINABLE BY SUCH PROCESS WARNER-LAMBERT COMPANY (US) 1997-10-16 WO claimed
EP-0525389-B1 Process for preparing mechanically stable, well disintegrating tablets from small active agent containing solid forms MERZ & CO GMBH & CO (DE) 1996-05-22 EP claimed
EP-0469328-B1 Process for the preparation of small controlled release particles with a high content of Etofibrat, its use and its orally administrable forms MERZ & CO GMBH & CO (DE) 1994-06-01 EP claimed
EP-0468247-B1 Process for the preparation of tablets mechanically stable and well-disintegrable, from small extrusion pellets with a high etofibrat content MERZ & CO GMBH & CO (DE) 1994-06-01 EP claimed
EP-0168360-B1 PROCESS FOR PREPARING ETOFIBRATE OR SIMILAR COMPOUNDS CONTAINING SUSTAINED RELEASE MICROGRANULES AND PRODUCTS THUS OBTAINED Valducci, Roberto (IT) 1992-06-10 EP claimed
US-4957746-A Process for preparing etofibrate or similar compounds containing sustained release microgranules and products thus obtained VALDUCCI ROBERTO (IT) 1990-09-18 US claimed
EP-0168360-A2 Process for preparing etofibrate or similar compounds containing sustained release microgranules and products thus obtained Valducci, Roberto (IT) 1986-01-15 EP claimed
US-4250191-A ADMINISTERING A PHENOXYACETIC ACID DERIVATIVE EDWARDS K DAVID 1981-02-10 US claimed
US-4028369-A Preparation of glycol (2-(p-chlorophenoxy)-2-methylpropionate)-2-nicotinate ALTER S.A. (ES) 1977-06-07 US claimed
US-4017502-A Process for purifying the mixed ester, ethylene glycol 1-(2-p-chlorophenoxy)-2-methylpropionate nicotinate ALTER, S.A. (ES) 1977-04-12 US claimed