Etofibrate

Etofibrate

SCHEMBL29801484

CC(C)(Oc1ccc(Cl)cc1)C(=O)OCCOC(=O)c1cccnc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.55
KMT2A Q03164 6/20 0.55
LMNA P02545 5/20 0.55
ALDH1A1 P00352 4/20 0.55
MEN1 O00255 2/20 0.55
USP2 O75604 1/20 0.55
CYP1A2 P05177 3/20 0.54
CYP3A4 P08684 2/20 0.54
TSHR P16473 2/20 0.54
ABCB11 O95342 1/20 0.54
HTR2A P28223 1/20 0.54
PMP22 Q01453 1/20 0.54
PPARA Q07869 1/20 0.54
CYP2C9 P11712 2/20 0.54
CYP2C19 P33261 2/20 0.54
SMN1; SMN2 Q16637 1/20 0.52
MAPT P10636 2/20 0.48
HPGD P15428 1/20 0.48
KDM4E B2RXH2 1/20 0.47
THRB P10828 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Etofibrate SCHEMBL8168409 1.00 L3MBTL1 (0.55) L3MBTL1KMT2ALMNAALDH1A1MEN1
Etofibrate SCHEMBL3122 1.00 L3MBTL1 (0.55) L3MBTL1KMT2ALMNAALDH1A1MEN1
Etofibrate SCHEMBL1649349 0.99 L3MBTL1 (0.54) L3MBTL1KMT2ALMNAALDH1A1MEN1
Ronifibrate SCHEMBL48852 0.96 L3MBTL1 (0.59) L3MBTL1KMT2ALMNAALDH1A1MEN1
Simfibrate SCHEMBL5808862 0.96 L3MBTL1 (0.59) L3MBTL1KMT2ALMNAALDH1A1MEN1
SCHEMBL10973734 0.92 L3MBTL1 (0.55) L3MBTL1KMT2ALMNAALDH1A1MEN1
Picafibrate SCHEMBL2109083 0.85 SMN1; SMN2 (0.65) KMT2ALMNAALDH1A1MEN1USP2
Binifibrate SCHEMBL49116 0.85 KMT2A (0.51) L3MBTL1KMT2ALMNAALDH1A1MEN1
Binifibrate SCHEMBL29388376 0.85 KMT2A (0.51) L3MBTL1KMT2ALMNAALDH1A1MEN1
SCHEMBL2615470 0.84 L3MBTL1 (0.59) L3MBTL1KMT2ALMNAALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115397412-B Modulators of MAS-related G protein receptor X4 and related products and methods 伊赛恩特制药公司 2025-03-25 CN disclosed
EP-3674298-B9 SUBSTITUTED INDAZOLES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL FORMULATIONS CONTAINING THEM, AND THEIR USE FOR THE PREPARATION OF MEDICAMENTS Bayer Pharma AG (DE) 2024-06-19 EP disclosed
EP-3674298-B1 SUBSTITUTED INDAZOLES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL FORMULATIONS CONTAINING THEM, AND THEIR USE FOR THE PREPARATION OF MEDICAMENTS Bayer Pharma AG (DE) 2024-01-10 EP disclosed
EP-4301728-A1 ARYLSULFOXAMIDES AS OREXIN RECEPTOR AGONISTS Research Triangle Institute (US) 2024-01-10 EP disclosed
US-11793777-B2 Methods and compositions for treating conditions associated with an abnormal inflammatory response FIRST WAVE BIO, INC. (US) 2023-10-24 US disclosed
EP-4260909-A2 SUBSTITUTED INDAZOLES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE IN THE PREPARATION OF DRUGS Bayer Pharma Aktiengesellschaft (DE) 2023-10-18 EP disclosed
CN-116568802-A In vitro method for preparing mature red blood cells 西湖生物医药科技(上海)有限公司 2023-08-08 CN disclosed
EP-4104838-A1 Use of DPP IV inhibitors Boehringer Ingelheim International GmbH (DE) 2022-12-21 EP disclosed
WO-2022187231-A1 ARYLSULFOXAMIDES AS OREXIN RECEPTOR AGONISTS RESEARCH TRIANGLE INSTITUTE (US) 2022-09-09 WO disclosed
EP-2397142-B1 Use of DPP IV inhibitors BOEHRINGER INGELHEIM INT (DE) 2022-07-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11793777-B2 Methods and compositions for treating conditions associated with an abnormal inflammatory response FH, CS, ECHS1 L3MBTL1 4635/4885KMT2A 3704/4885LMNA 3341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.