Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 3/20 | 0.53 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.53 |
| ▸ | CACNA1I | Q9P0X4 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | PDE8B | O95263 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3704214 | 0.87 | CACNA1G (0.57) | CACNA1GCACNA1HCACNA1IALDH1A1HDAC1 | |
| SCHEMBL1906943 | 0.86 | KMT2A (0.60) | CACNA1GCACNA1HCACNA1IALDH1A1HDAC1 | |
| SCHEMBL4726770 | 0.84 | SMN1; SMN2 (0.50) | CACNA1GCACNA1HCACNA1IALDH1A1HDAC1 | |
| SCHEMBL29705220 | 0.83 | CACNA1G (0.54) | CACNA1GCACNA1HCACNA1IALDH1A1HDAC1 | |
| SCHEMBL8865422 | 0.82 | CACNA1G (0.49) | CACNA1GCACNA1HCACNA1IALDH1A1HDAC1 | |
| SCHEMBL1047744 | 0.81 | CACNA1G (0.55) | CACNA1GCACNA1HCACNA1IALDH1A1HDAC1 | |
| SCHEMBL4288842 | 0.80 | HDAC1 (0.56) | CACNA1GCACNA1HCACNA1IALDH1A1HDAC1 | |
| SCHEMBL16554654 | 0.80 | SCD (0.57) | ALDH1A1HDAC1KMT2ANPC1RAB9A | |
| SCHEMBL4676077 | 0.79 | CACNA1G (0.50) | CACNA1GCACNA1HCACNA1IALDH1A1HDAC1 | |
| SCHEMBL166508 | 0.77 | ALDH1A1 (0.53) | CACNA1GCACNA1HCACNA1IALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078127-A1 | HETEROBICYCLIC AMIDES AS INHIBITORS OF CD38 | BOEHRINGER INGELHEIM INT (DE) | 2026-03-19 | — | — | US | disclosed |
| US-20240368167-A1 | HETEROBICYCLIC AMIDES AS INHIBITORS OF CD38 | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240368167-A1 | HETEROBICYCLIC AMIDES AS INHIBITORS OF CD38 | CD38, PARP12, ENTPD2 | CACNA1G 3166/4885CACNA1H 3394/4885CACNA1I 2195/4885 |
| US-20260078127-A1 | HETEROBICYCLIC AMIDES AS INHIBITORS OF CD38 | CD38, CD22, CD79B | CACNA1G 1189/4885CACNA1H 1127/4885CACNA1I 1479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.