Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL31744981 | 0.68 | MAPK1 (0.41) | KDM4EALDH1A1MAPTMAPK1PKM | |
| Trifluoroacetic Acid SCHEMBL31745068 | 0.67 | L3MBTL1 (0.39) | KDM4ENPSR1ALDH1A1MAPTHSD17B10 | |
| SCHEMBL31744975 | 0.67 | ADORA1 (0.47) | ALDH1A1HSD17B10TSHRKMT2ACASP1 | |
| SCHEMBL31745046 | 0.66 | PNP (0.39) | KDM4EALDH1A1MAPTSMN1; SMN2HPGD | |
| SCHEMBL30401926 | 0.66 | ALDH1A1 (0.35) | KDM4ENPSR1RXFP1ALDH1A1MAPT | |
| Formic Acid SCHEMBL31744989 | 0.66 | ADORA2A (0.42) | ALDH1A1MAPTHPGDALOX15HSD17B10 | |
| SCHEMBL29829364 | 0.65 | PNP (0.40) | KDM4EALDH1A1MAPTSMN1; SMN2HPGD | |
| Trifluoroacetic Acid SCHEMBL7415089 | 0.65 | MLYCD (0.47) | ALDH1A1HSD17B10TSHRPOLBGAA | |
| SCHEMBL23498695 | 0.65 | MEN1 (0.44) | KDM4ENPSR1RXFP1ALDH1A1MAPT | |
| SCHEMBL29999189 | 0.65 | AURKA (0.45) | KDM4ENPSR1RXFP1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240374602-A1 | METHODS FOR TREATING NEUROGENERATIVE DISEASES | PTC THERAPEUTICS, INC. | 2024-11-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240374602-A1 | METHODS FOR TREATING NEUROGENERATIVE DISEASES | MAPT, MAP1B, MAP2 | KDM4E 4099/4885NPSR1 1927/4885RXFP1 4864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.