SCHEMBL31221982

SCHEMBL31221982

CNC(=O)CCN(Cc1cccc(F)n1)C(=O)c1sc2ccc(-c3ccc(=O)n(C)c3)cc2c1C

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 2/20 0.33
BRD4 O60885 2/20 0.32
ADORA2A P29274 3/20 0.31
ADORA2B P29275 1/20 0.31
ADORA1 P30542 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31222041 0.88 SOS1 (0.33) SOS1BRD4
SCHEMBL31222063 0.88 CREBBP (0.40) BRD4
SCHEMBL31221953 0.85 CREBBP (0.35) SOS1BRD4
SCHEMBL31221945 0.83 PIK3CD (0.41)
SCHEMBL31221986 0.82 PKM (0.30)
SCHEMBL31221914 0.80 CREBBP (0.34) BRD4
SCHEMBL31222005 0.79 BRD4 (0.33) BRD4
SCHEMBL31221926 0.79 CASP3 (0.32) BRD4
SCHEMBL31221904 0.79 HTR6 (0.34) BRD4
SCHEMBL31221907 0.78 LMNA (0.37) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024232599-A1 NOVEL BENZOTHIOPHENE DERIVATIVE INHIBITING BET PROTEIN AND COMPOSITION FOR TREATMENT OF CANCER, USING SAME 주식회사 베노바이오 2024-11-14 WO disclosed