Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | PLEC | Q15149 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2896486 | 0.90 | ALDH1A1 (0.62) | ALDH1A1HSD17B10GAAMAPTHPGD | |
| SCHEMBL10597819 | 0.87 | ALDH1A1 (0.58) | ALDH1A1HSD17B10GAAMAPTHPGD | |
| SCHEMBL11693736 | 0.87 | LMNA (0.57) | ALDH1A1HSD17B10GAAMAPTHPGD | |
| SCHEMBL827667 | 0.85 | TSHR (0.58) | ALDH1A1HSD17B10KDM4ELMNACYP1A2 | |
| SCHEMBL9008367 | 0.83 | TSHR (0.56) | ALDH1A1HSD17B10KDM4ELMNACYP1A2 | |
| SCHEMBL6227901 | 0.83 | HRH3 (0.52) | ALDH1A1HSD17B10KDM4ELMNACYP1A2 | |
| SCHEMBL27547872 | 0.83 | ALDH1A1 (0.54) | ALDH1A1HSD17B10GAAMAPTHPGD | |
| SCHEMBL29649164 | 0.83 | ALDH1A1 (0.57) | ALDH1A1HSD17B10GAAMAPTHPGD | |
| SCHEMBL6044437 | 0.82 | CA12 (0.68) | ALDH1A1HSD17B10GAAMAPTKDM4E | |
| SCHEMBL17694807 | 0.82 | HRH3 (0.51) | ALDH1A1HSD17B10GAAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119101935-A | Platinum-based self-supporting membrane catalyst, preparation method and application thereof in electrocatalytic hydrogen evolution | 南通大学 | 2024-12-10 | — | — | CN | disclosed |
| CN-118026872-A | 2-Amino dimethyl terephthalate eutectic and preparation method thereof | 天津大学 | 2024-05-14 | — | — | CN | disclosed |
| CN-118026870-A | 2-Amino dimethyl terephthalate-tetracyanobenzene eutectic crystal and preparation method and application thereof | 天津大学 | 2024-05-14 | — | — | CN | disclosed |
| CN-115491051-A | Preparation method and application of pigment yellow 155 | 德州学院 | 2022-12-20 | — | — | CN | disclosed |
| CN-106970509-B | Toner, developer, toner cartridge, process cartridge, image forming apparatus and image forming method | 富士施乐株式会社 | 2020-06-19 | — | — | CN | disclosed |
| EP-1724263-B1 | BASIC AMINE COMPOUND AND USE THEREOF | KUREHA CORP (JP) | 2014-03-05 | — | — | EP | disclosed |
| US-20120035194-A1 | SUBSTITUTED 2-AMINO-FUSED HETEROCYCLIC COMPOUNDS | PFIZER INC. (US) | 2012-02-09 | — | — | US | disclosed |
| US-7998978-B2 | Substituted 2-amino-fused heterocyclic compounds | PFIZER INC. (US) | 2011-08-16 | — | — | US | disclosed |
| US-20110172212-A1 | AMINE-BASED COMPOUND AND USE THEREOF | KUREHA CORPORATION (JP) | 2011-07-14 | — | — | US | disclosed |
| US-7968719-B2 | Indazole derivatives as inhibitors of hormone sensitive lipase | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2011-06-28 | — | — | US | disclosed |
| US-5616778-A | Modified form of bis-1,4-[2'-(2\",5\"-dimethoxycarbonylphenylazo)-3'-oxobutyramido]benzene and process for its synthesis | SANDOZ LTD. (CH) | 1997-04-01 | — | — | US | disclosed |
| US-5420145-A | Antileukemia | Shudo, Koichi (JP) | 1995-05-30 | — | — | US | disclosed |
| EP-0617020-A1 | Carboxylic acid derivatives having retinoic acid-like activity | Shudo, Koichi, Prof. Dr. (JP) | 1994-09-28 | — | — | EP | disclosed |
| US-5030247-A | Mixtures of disazo compounds containing two phenyl diazo component radicals having one or two (C1-4 alkoxy)carbonyl groups and a bis-acetoacetamido-arylene coupling radical | SANDOZ LTD. (CH) | 1991-07-09 | — | — | US | disclosed |
| US-4379913-A | Compositions useful as internal antistatic additives for polymeric structures | DIAMOND SHAMROCK CORPORATION (US) | 1983-04-12 | — | — | US | disclosed |
| US-4222788-A | Mixed pigment and process of preparing the same | BASF FARBEN & FASERN AG (DE) | 1980-09-16 | — | — | US | disclosed |
| US-4136033-A | DIAZO COUPLERS | SANDOZ LTD. (CH) | 1979-01-23 | — | — | US | disclosed |
| US-4003886-A | Tetracarboxylic acid ester substituted disazo pigments | CIBA-GEIGY AG (CH) | 1977-01-18 | — | — | US | disclosed |
| US-3997521-A | PIGMENTS | SANDOZ LTD. (CH) | 1976-12-14 | — | — | US | disclosed |
| US-3985711-A | Dicarboxylic compounds having 2,4-quinazolinedione rings and polyester resins derived therefrom | INSTITUT FRANCAIS DU PETROLE, DES CARBURANTS ET LUBRIFIANTS ET ENTREPRISE DE RECHERCHES ET D'ACTIVITIES PETROLIERES ELF (FR) | 1976-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035194-A1 | SUBSTITUTED 2-AMINO-FUSED HETEROCYCLIC COMPOUNDS | MAPK1, SLC5A1, ATF1 | ALDH1A1 1098/4885HSD17B10 2447/4885GAA 2711/4885 |
| US-20110172212-A1 | AMINE-BASED COMPOUND AND USE THEREOF | NR0B2, NR5A2, NR1D2 | ALDH1A1 2045/4885HSD17B10 608/4885GAA 4793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.