SCHEMBL31222060

SCHEMBL31222060

CNC(=O)CCN(Cc1ccnn1C)C(=O)c1sc2cc(-c3ccc(=O)n(C)c3)ccc2c1C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31221876 0.81
SCHEMBL31221953 0.79 CREBBP (0.35)
SCHEMBL31222063 0.79 CREBBP (0.40)
SCHEMBL31221986 0.79 PKM (0.30)
SCHEMBL31221922 0.78 PIK3CG (0.36)
SCHEMBL31221982 0.76 SOS1 (0.33)
SCHEMBL31221914 0.76 CREBBP (0.34)
SCHEMBL31221907 0.75 LMNA (0.37)
SCHEMBL31222005 0.75 BRD4 (0.33)
SCHEMBL31221904 0.74 HTR6 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024232599-A1 NOVEL BENZOTHIOPHENE DERIVATIVE INHIBITING BET PROTEIN AND COMPOSITION FOR TREATMENT OF CANCER, USING SAME 주식회사 베노바이오 2024-11-14 WO disclosed