Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9611270 | 0.84 | KMT2A (0.62) | SMN1; SMN2KMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL2092441 | 0.81 | NPSR1 (0.48) | SMN1; SMN2KMT2AMTNR1AMTNR1BNPSR1 | |
| SCHEMBL31222334 | 0.80 | RIPK1 (0.46) | SMN1; SMN2KMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL2092439 | 0.80 | NPSR1 (0.47) | SMN1; SMN2KMT2AMTNR1AMTNR1BNPSR1 | |
| SCHEMBL7388597 | 0.78 | MTNR1A (0.46) | SMN1; SMN2KMT2AMTNR1AMTNR1BNPSR1 | |
| SCHEMBL30881933 | 0.75 | NPSR1 (0.54) | SMN1; SMN2KMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL2880320 | 0.75 | HDAC4 (0.54) | SMN1; SMN2KMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL67323 | 0.73 | MTNR1A (0.44) | SMN1; SMN2KMT2AMEN1MTNR1AMTNR1B | |
| SCHEMBL23032194 | 0.71 | HSD17B1 (0.45) | SMN1; SMN2KMT2AMEN1CYP3A4CYP2C9 | |
| SCHEMBL14362033 | 0.70 | NPSR1 (0.58) | SMN1; SMN2KMT2AMEN1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118993825-A | Method for preparing aromatic thioether derivative by promoting copper-mediated aryl C-H bond vulcanization by organic acid | 安徽工业大学 | 2024-11-22 | — | — | CN | disclosed |