Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30881933 | 0.84 | NPSR1 (0.54) | KMT2AMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31222331 | 0.84 | SMN1; SMN2 (0.47) | KMT2AMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11504157 | 0.83 | NPSR1 (0.52) | KMT2AMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11583122 | 0.83 | KMT2A (0.58) | KMT2AMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11032674 | 0.81 | KMT2A (0.53) | KMT2AMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8946139 | 0.80 | KMT2A (0.60) | KMT2AMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3283283 | 0.80 | KMT2A (0.60) | KMT2AMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28240299 | 0.79 | KMT2A (0.50) | KMT2AMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL12848104 | 0.79 | RIPK1 (0.57) | KMT2AMEN1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL14362033 | 0.79 | NPSR1 (0.58) | KMT2AMEN1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114031477-B | Method for reducing amide compounds into amine compounds by cobalt catalysis | 浙江工业大学 | 2023-12-05 | — | — | CN | disclosed |
| CN-114031477-A | Method for reducing amide compounds into amine compounds by cobalt catalysis | 浙江工业大学 | 2022-02-11 | — | — | CN | disclosed |
| US-20210054007-A1 | RECEPTOR INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | BEIJING TIDE PHARMACEUTICAL CO., LTD. (CN) | 2021-02-25 | — | — | US | disclosed |
| US-10646490-B2 | Thieno- and pyrrolopyrimidine analogues and prodrugs thereof as anticancer agents and methods of use thereof | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (US) | 2020-05-12 | — | — | US | disclosed |
| US-20190160071-A1 | THIENO- AND PYRROLOPYRIMIDINE ANALOGUES AND PRODRUGS THEREOF AS ANTICANCER AGENTS AND METHODS OF USE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY | 2019-05-30 | — | — | US | disclosed |
| US-8415486-B2 | IAP inhibitors | TETRALOGIC PHARMACEUTICALS CORP. (US) | 2013-04-09 | — | — | US | disclosed |
| US-8415486-B2 | IAP inhibitors | TETRALOGIC PHARMACEUTICALS CORP. (US) | 2013-04-09 | — | — | US | disclosed |
| US-20120135990-A1 | IAP INHIBITORS | TETRALOGIC PHARMACEUTICALS CORP. (US) | 2012-05-31 | — | — | US | disclosed |
| US-20110053901-A1 | ACETYL MIMIC COMPOUNDS FOR THE INHIBITION OF ISOPRENYL-S-CYSTEINYL METHYLTRANSFERASE | SIGNUM BIOSCIENCES, INC. (US) | 2011-03-03 | — | — | US | disclosed |
| US-20110053901-A1 | ACETYL MIMIC COMPOUNDS FOR THE INHIBITION OF ISOPRENYL-S-CYSTEINYL METHYLTRANSFERASE | SIGNUM BIOSCIENCES, INC. (US) | 2011-03-03 | — | — | US | disclosed |
| US-20100247461-A1 | ANTI-INFLAMMATORY COMPLEXES | SIGNUM BIOSCIENCES, INC. (US) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190160071-A1 | THIENO- AND PYRROLOPYRIMIDINE ANALOGUES AND PRODRUGS THEREOF AS ANTICANCER AGENTS AND METHODS OF USE THEREOF | TYMP, TK1, TYMS | KMT2A 2096/4885MEN1 3219/4885CYP3A4 159/4885 |
| US-20120135990-A1 | IAP INHIBITORS | XIAP, IAPP, BIRC5 | KMT2A 4485/4885MEN1 2419/4885CYP3A4 3818/4885 |
| US-20210054007-A1 | RECEPTOR INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | TACR1, TACR2, GPBAR1 | KMT2A 3517/4885MEN1 2752/4885CYP3A4 333/4885 |
| US-20110053901-A1 | ACETYL MIMIC COMPOUNDS FOR THE INHIBITION OF ISOPRENYL-S-CYSTEINYL METHYLTRANSFERASE | MPO, CYSLTR1, HNMT | KMT2A 983/4885MEN1 4170/4885CYP3A4 1189/4885 |
| US-10646490-B2 | Thieno- and pyrrolopyrimidine analogues and prodrugs thereof as anticancer agents and methods of use thereof | TYMP, TK1, TYMS | KMT2A 2096/4885MEN1 3219/4885CYP3A4 159/4885 |
| US-20100247461-A1 | ANTI-INFLAMMATORY COMPLEXES | SSB, NFKBIA, FABP1 | KMT2A 4764/4885MEN1 4705/4885CYP3A4 1024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.