SCHEMBL31222364

SCHEMBL31222364

CC(C)C[C@H](NC(=O)[C@H](Cc1ccc([N+](=O)[O-])cc1)NC(=O)CN(C)C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 1/20 0.48
▸ OPRD1 P41143 7/20 0.47
▸ OPRM1 P35372 2/20 0.47
▸ NPY1R P25929 1/20 0.46
▸ NPY2R P49146 1/20 0.46
▸ NPY4R P50391 1/20 0.46
▸ MMP2 P08253 1/20 0.42
▸ ACE P12821 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31222363 0.88 NPY4R (0.58) NPY1RNPY2RNPY4R
SCHEMBL31222367 0.88 FOLH1 (0.51) FOLH1OPRD1OPRM1NPY1RNPY2R
SCHEMBL31222371 0.88 FOLH1 (0.51) FOLH1OPRD1OPRM1NPY1RNPY2R
SCHEMBL31222361 0.84 NPY4R (0.64) NPY1RNPY2RNPY4R
SCHEMBL31222372 0.84 NPY4R (0.64) NPY1RNPY2RNPY4R
SCHEMBL11136648 0.84 OPRD1 (0.62) OPRD1OPRM1
SCHEMBL1371080 0.83 OPRD1 (0.48) OPRD1OPRM1NPY1RNPY2RNPY4R
SCHEMBL31222368 0.81 NPY4R (0.62) NPY1RNPY2RNPY4R
SCHEMBL31222391 0.80 NPY4R (0.61) NPY1RNPY2RNPY4R
SCHEMBL31222418 0.80 NPY4R (0.61) NPY1RNPY2RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240301023-A1 PEPTIDES AND USES THEREOF PreveCeutical Medical Inc. (CA) 2024-09-12 — — US claimed
US-20240301023-A1 PEPTIDES AND USES THEREOF PreveCeutical Medical Inc. (CA) 2024-09-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240301023-A1 PEPTIDES AND USES THEREOF OPRL1, OPRK1, OPRM1 FOLH1 573/4885OPRD1 4/4885OPRM1 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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