SCHEMBL312235

SCHEMBL312235

[c]1c(C2=CC=CC2)ccc2c1Cc1ccccc1-2

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAOA P21397 2/20 0.30
CYP1A2 P05177 1/20 0.30
ADRA2A P08913 1/20 0.30
SLC6A2 P23975 1/20 0.30
HTR2C P28335 1/20 0.30
SLC6A4 P31645 1/20 0.30
HTR2B P41595 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7708872 0.77 KDM4E (0.31) KDM4ENPC1ALDH1A1LMNAMAPT
SCHEMBL217877 0.75 ALDH1A1 (0.36) SRD5A2KDM4ENPC1ALDH1A1LMNA
SCHEMBL216860 0.74 ALDH1A1 (0.38) SRD5A2KDM4ENPC1ALDH1A1LMNA
SCHEMBL9064847 0.74 CYP1A2 (0.30) CYP1A2
SCHEMBL3444458 0.72 CYP1A2 (0.30) MAOACYP1A2ADRA2ASLC6A2HTR2C
SCHEMBL2965677 0.72 ALDH1A1 (0.36) SRD5A2KDM4ENPC1ALDH1A1LMNA
SCHEMBL313500 0.72 PNMT (0.44) SRD5A2KDM4ENPC1ALDH1A1LMNA
SCHEMBL2974521 0.72 KDM4E (0.36) SRD5A2KDM4ENPC1ALDH1A1LMNA
SCHEMBL217598 0.72 PNMT (0.37) SRD5A2KDM4ENPC1ALDH1A1LMNA
SCHEMBL2964837 0.72 KDR (0.42) SRD5A2KDM4ENPC1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 627 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9683056-B2 Activating agents for hafnium-based metallocene components TOTAL RESEARCH & TECHNOLOGY FELUY (BE) 2017-06-20 US claimed
US-20160032024-A1 Activating Agents for Hafnium-Based Metallocene Components TOTAL RES & TECHNOLOGY FELUY (BE) 2016-02-04 US claimed
EP-1809675-B1 POLYOLEFINS PREPARED FROM A METALLOCENE AND A NEW SINGLE SITE CATALYST COMPONENTS IN A SINGLE REACTOR TOTAL RES & TECHNOLOGY FELUY (BE) 2013-04-03 EP claimed
CN-101765461-B Preparation of activating support TOTAL PETROCHEMICALS RES FELUY 2012-09-05 CN claimed
US-8093418-B2 Metallocenes; for production of ethylene/propylene homo-/copolymers FINA TECHNOLOGY, INC. (US) 2012-01-10 US claimed
JP-2009544819-A 2009-12-17 JP claimed
EP-2044131-A2 FLUORENYL CATALYST COMPOSITIONS AND OLEFIN POLYMERIZATION PROCESS Fina Technology, Inc. (US) 2009-04-08 EP claimed
JP-2009504888-A 2009-02-05 JP claimed
US-7449527-B2 Polyolefin production TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2008-11-11 US claimed
US-20080108766-A1 Polyolefins Prepared From A Metallocene And A New Single Site Catalyst Component In A Single Reactor TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2008-05-08 US claimed
CN-1190657-A Process for producing stereospecific polymers FINA TECHNOLOGY (US) 1998-08-19 CN claimed
CN-1185445-A Catalyst yield enhancement with supported metallocene catalysts FINA TECHNOLOGY CO LTD (US) 1998-06-24 CN claimed
CN-1033457-C Preparation of metallocene catalysts for polymerization of olefins FINA TECHNOLOGY (US) 1996-12-04 CN claimed
CN-1105673-A Preparation of metallocene catalysts for polymerization of olefins FINA TECHNOLOGY (US) 1995-07-26 CN claimed
CN-1028641-C Preparation of metallocene catalysts for polymerization of olefins FINA TECHNOLOGY (US) 1995-05-31 CN claimed
US-5225500-A Coordination catalyst FINA TECHNOLOGY, INC. (US) 1993-07-06 US claimed
US-5196496-A Zirconium or hafnium catalysts HIMONT INCORPORATED (US) 1993-03-23 US claimed
US-5155080-A Metallocene catalyst FINA TECHNOLOGY, INC. (US) 1992-10-13 US claimed
CN-1051311-A Preparation of metallocene catalysts for polymerization of olefins FINA TECHNOLOGY (US) 1991-05-15 CN claimed
CN-1040036-A Produce the method and the catalyzer of syndiotactic polyolefins FINA TECHNOLOGY (US) 1990-02-28 CN claimed