Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.57 |
| ▸ | RAB9A | P51151 | 8/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.53 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7549644 | 0.84 | ACHE (0.64) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL62491 | 0.84 | RAB9A (0.62) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL7549579 | 0.82 | NPC1 (0.53) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL2178266 | 0.79 | NPC1 (0.88) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL29386825 | 0.79 | NPC1 (0.88) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL8390651 | 0.78 | PKN1 (0.60) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL8390646 | 0.78 | RHEB (0.53) | KDM4EALDH1A1HPGDMAPTPKN1 | |
| SCHEMBL24295036 | 0.78 | NPC1 (0.84) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL13137726 | 0.77 | NPC1 (0.66) | NPC1RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL60856 | 0.77 | AURKA (0.66) | NPC1RAB9AGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118908896-A | 4- (1H-benzo [ d ] imidazole-2-yl) -N, N-bis (2-chloroethyl) aniline derivative and preparation method and application thereof | 广东海洋大学 | 2024-11-08 | — | — | CN | claimed |
| CN-118908896-B | 4- (1H-benzo [ d ] imidazole-2-yl) -N, N-bis (2-chloroethyl) aniline derivative and preparation method and application thereof | 广东海洋大学 | 2026-01-06 | — | — | CN | disclosed |
| CN-118908896-B | 4- (1H-benzo [ d ] imidazole-2-yl) -N, N-bis (2-chloroethyl) aniline derivative and preparation method and application thereof | 广东海洋大学 | 2026-01-06 | — | — | CN | disclosed |
| CN-118908896-A | 4- (1H-benzo [ d ] imidazole-2-yl) -N, N-bis (2-chloroethyl) aniline derivative and preparation method and application thereof | 广东海洋大学 | 2024-11-08 | — | — | CN | disclosed |
| CN-118908896-A | 4- (1H-benzo [ d ] imidazole-2-yl) -N, N-bis (2-chloroethyl) aniline derivative and preparation method and application thereof | 广东海洋大学 | 2024-11-08 | — | — | CN | disclosed |
| CN-118908896-A | 4- (1H-benzo [ d ] imidazole-2-yl) -N, N-bis (2-chloroethyl) aniline derivative and preparation method and application thereof | 广东海洋大学 | 2024-11-08 | — | — | CN | disclosed |