SCHEMBL60856

SCHEMBL60856

CN(C)c1ccc(-c2nc3ccccc3[nH]2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AURKA O14965 2/20 0.66
NPC1 O15118 9/20 0.66
RAB9A P51151 9/20 0.66
GAA P10253 1/20 0.66
KDM4E B2RXH2 8/20 0.64
MAPT P10636 2/20 0.64
GUSB P08236 1/20 0.64
TCF4 P15884 1/20 0.64
CTNNB1 P35222 1/20 0.64
SMN1; SMN2 Q16637 6/20 0.63
ALDH1A1 P00352 6/20 0.63
HPGD P15428 3/20 0.63
TP53 P04637 2/20 0.63
HSD17B10 Q99714 2/20 0.63
POLB P06746 2/20 0.63
GFER P55789 1/20 0.63
PKM P14618 4/20 0.62
HDAC6 Q9UBN7 1/20 0.62
PKN1 Q16512 1/20 0.60
PKN2 Q16513 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL484174 0.98 AURKA (0.64) AURKANPC1RAB9AGAAKDM4E
SCHEMBL13085648 0.87 NPC1 (0.67) AURKANPC1RAB9AGAAKDM4E
SCHEMBL484484 0.86 NPC1 (0.61) AURKANPC1RAB9AGAAKDM4E
SCHEMBL29386825 0.86 NPC1 (0.88) NPC1RAB9AGAAKDM4EMAPT
SCHEMBL2178266 0.86 NPC1 (0.88) NPC1RAB9AGAAKDM4EMAPT
SCHEMBL62491 0.84 RAB9A (0.62) NPC1RAB9AGAAKDM4EMAPT
SCHEMBL24295036 0.84 NPC1 (0.84) NPC1RAB9AGAAKDM4EMAPT
SCHEMBL13836671 0.83 TCF4 (0.64) AURKANPC1RAB9AKDM4EMAPT
SCHEMBL8767834 0.83 TCF4 (0.78) AURKANPC1RAB9AGAAKDM4E
SCHEMBL19073834 0.83 NPC1 (0.57) NPC1RAB9AGAAKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 281 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7470827-B2 Composition for the vapor phase dehydrohalogenation of 1,1,2-trihaloethane to 1,1-dihaloethylene and methods for preparing and using such composition PPG INDUSTRIES OHIO, INC. (US) 2008-12-30 US claimed
US-20080242902-A1 Composition For the Vapor Phase Dehydrohalogenation of 1,1,2-Trihaloethane To 1,1-Dihaloethylene and Methods For Preparing and Using Such Composition PPG INDUSTRIES OHIO, INC (US) 2008-10-02 US claimed
US-20070148185-A1 Novel therapeutic target for protozoal diseases VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY 2007-06-28 US claimed
WO-2007047579-A2 A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2007-04-26 WO claimed
WO-2006132625-A1 COMPOSITION FOR THE VAPOR PHASE DEHYDROHALOGENATION OF 1,1,2-TRIHALOETHANE TO 1,1-DIHALOETHYLENE AND METHODS FOR PREPARING AND USING SUCH COMPOSITIONS PPG INDUSTRIES OHIO, INC. (US) 2006-12-14 WO claimed
EP-4257623-B1 PHOTOSENSITIVE POLYIMIDE RESIN COMPOSITION, RESIN FILM, AND ELECTRONIC DEVICE MITSUBISHI GAS CHEMICAL CO (JP) 2026-05-27 EP disclosed
CN-122029488-A Photosensitive coloring composition, cured product, partition wall, organic electroluminescent element, color filter, and image display device 三菱化学株式会社 2026-05-12 CN disclosed
US-12441842-B2 Polyimide resin, photosensitive resin composition, resin film, and electronic device MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2025-10-14 US disclosed
CN-112313579-B Photosensitive colored resin composition, cured product, image display device, and illumination 三菱化学株式会社 2025-05-13 CN disclosed
CN-119948406-A Photosensitive colored resin composition, cured product, partition wall, organic electroluminescent element, color filter, and image display device 三菱化学株式会社 2025-05-06 CN disclosed
WO-2025084352-A1 PHOTOSENSITIVE COLORED COMPOSITION, CURED PRODUCT, PARTITION WALL, ORGANIC ELECTROLUMINESCENT ELEMENT, COLOR FILTER, AND IMAGE DISPLAY DEVICE 三菱ケミカル株式会社 2025-04-24 WO disclosed
WO-2025084407-A1 PHOTOSENSITIVE COLORING COMPOSITION, CURED PRODUCT, PARTITION WALL, ORGANIC ELECTROLUMINESCENT ELEMENT, IMAGE DISPLAY DEVICE, AND PIGMENT DISPERSION LIQUID 三菱ケミカル株式会社 2025-04-24 WO disclosed
US-4960663-A PHOTOCONDUCTOR, PHOTOINITIATOR AND ACTATE OF PHENOLIC HYDROXYL-CONTAINING RESIN DISPERSED IN A RESINOUS MATRIX; XEROGRAPHY; PLATES POLYCHROME CORPORATION (US) 1990-10-02 US disclosed
EP-0385376-A2 Persistent photoconductive coating composition Polychrome Corporation (US) 1990-09-05 EP disclosed
EP-0138187-B1 PHOTOPOLYMERIZABLE COMPOSITION MITSUBISHI KASEI CORPORATION (JP) 1989-01-11 EP disclosed
US-4594310-A Photopolymerizable composition comprising tertiary aromatic amine and hexaarylbiimazole initiators MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) 1986-06-10 US disclosed
EP-0138187-A2 Photopolymerizable composition MITSUBISHI KASEI CORPORATION (JP) 1985-04-24 EP disclosed
US-4033769-A Persistent photoconductive compositions XEROX CORPORATION (US) 1977-07-05 US disclosed
US-3961954-A Acid sensitized charge transfer complexes and cyclic electrostatographic imaging XEROX CORPORATION (US) 1976-06-08 US disclosed
US-3932025-A Imaging system XEROX CORPORATION (US) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080242902-A1 Composition For the Vapor Phase Dehydrohalogenation of 1,1,2-Trihaloethane To 1,1-Dihaloethylene and Methods For Preparing and Using Such Composition CYP2E1, CYP1A1, HDHD5 AURKA 1905/4885NPC1 2698/4885RAB9A 3877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.