Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL31224930 | 0.86 | SMN1; SMN2 (0.38) | KMT2AMEN1LMNAHPGDMAPT | |
| SCHEMBL31224735 | 0.85 | KMT2A (0.46) | KMT2AMEN1LMNAHPGDAHR | |
| SCHEMBL31224632 | 0.82 | ATAD2 (0.43) | HPGDMAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL31224620 | 0.81 | GABRG2 (0.48) | HPGDMAPTALDH1A1SMN1; SMN2GAA | |
| SCHEMBL31225030 | 0.79 | CYP11B2 (0.47) | ALDH1A1GAA | |
| SCHEMBL31224643 | 0.78 | POLB (0.46) | KMT2AMEN1LMNAHPGDAHR | |
| SCHEMBL8413415 | 0.74 | HTT (0.56) | KMT2AMEN1HPGDMAPTRECQL | |
| SCHEMBL310242 | 0.73 | MAPT (0.53) | KMT2AMEN1LMNAMAPTRECQL | |
| SCHEMBL8413418 | 0.72 | HTT (0.51) | KMT2AMEN1MAPTRECQLPOLB | |
| Lithium Ion SCHEMBL31224915 | 0.71 | SMN1; SMN2 (0.39) | KMT2AMEN1LMNAMAPTIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676926-A1 | BICYCLIC HETEROARYL COMPOUNDS FOR USE AS GPR35 MODULATORS | ThirtyFiveBio Limited (GB) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024184650-A1 | BICYCLIC HETEROARYL COMPOUNDS FOR USE AS GPR35 MODULATORS. | ThirtyFiveBio Limited (GB) | 2024-09-12 | — | — | WO | disclosed |