Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 9/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31224868 | 0.87 | LDHA (0.41) | ALPLALDH1A1KDM4EMAP2K4MAPK1 | |
| SCHEMBL31224620 | 0.84 | GABRG2 (0.48) | MAPTRAB9ANPC1ALDH1A1GAA | |
| SCHEMBL31225030 | 0.82 | CYP11B2 (0.47) | ALPLALDH1A1GAAATMHPGDS | |
| SCHEMBL31224836 | 0.82 | KMT2A (0.45) | MAPTALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL31224724 | 0.72 | ROCK2 (0.42) | MAPTRAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL8410461 | 0.72 | ATAD2 (0.60) | ATAD2MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL31224840 | 0.71 | CSNK1D (0.38) | RAB9ANPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL31224823 | 0.71 | MAP2K4 (0.47) | RAB9ANPC1ALDH1A1KDM4EHPGD | |
| SCHEMBL310982 | 0.70 | ATAD2 (0.51) | ATAD2MAPTRAB9ANPC1ALPL | |
| SCHEMBL357302 | 0.69 | ATAD2 (0.47) | ATAD2MAPTRAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4676926-A1 | BICYCLIC HETEROARYL COMPOUNDS FOR USE AS GPR35 MODULATORS | ThirtyFiveBio Limited (GB) | 2026-01-14 | — | — | EP | disclosed |
| WO-2024184650-A1 | BICYCLIC HETEROARYL COMPOUNDS FOR USE AS GPR35 MODULATORS. | ThirtyFiveBio Limited (GB) | 2024-09-12 | — | — | WO | disclosed |